Reactome | POLL [nucleoplasm]

POLL [nucleoplasm]

Stable Identifier

R-HSA-5687352

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA polymerase lambda, DNA polymerase beta-2, Pol beta2, DNA polymerase kappa

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UGP5 POLL

Gene Names

POLL

Chain

chain:1-575

Reference Genes

BioGPS Gene:27343 POLL

COSMIC (genes):POLL POLL

CTD Gene:27343 POLL

dbSNP Gene:27343 POLL

ENSEMBL:ENSG00000166169 POLL

ENSEMBL_homo_sapiens_GENE:ENSG00000166169.17 POLL

HGNC:9184 POLL

KEGG Gene (Homo sapiens):27343 POLL

Monarch:27343 POLL

NCBI Gene:27343 POLL

OMIM:606343 POLL

UCSC:Q9UGP5 POLL

Reference Transcript

Other Identifiers

11720777_x_at

11748194_a_at

11748769_a_at

11749030_x_at

11751320_a_at

11755961_x_at

16717706

221049_PM_s_at

221049_s_at

27343

3303878

3303879

3303880

3303881

3303882

3303884

3303885

3303887

3303890

3303891

3303893

3303894

3303896

3303897

3303900

3303901

3303903

3303904

3303905

3303906

57684_at

7935865

A_23_P97889

A_33_P3282669

A_33_P3326423

GE55220

GO:0000724

GO:0002376

GO:0003677

GO:0003824

GO:0003887

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006259

GO:0006260

GO:0006281

GO:0006287

GO:0006289

GO:0006303

GO:0006310

GO:0006974

GO:0016446

GO:0016740

GO:0016779

GO:0016829

GO:0034061

GO:0035861

GO:0043226

GO:0046872

GO:0048856

GO:0051575

GO:0071897

GO:0140097

HMNXSV003051059

ILMN_1745787

PH_hs_0029169

TC10001607.hg

TC10002807.hg

g7019490_3p_a_at

Participates

as a member of

POLL,POLM [nucleoplasm] (Homo sapiens)

Inferred To

POLL [nucleoplasm] (Bos taurus)

POLL [nucleoplasm] (Canis familiaris)

POLL [nucleoplasm] (Gallus gallus)

POLL [nucleoplasm] (Mus musculus)

POLL [nucleoplasm] (Rattus norvegicus)

POLL [nucleoplasm] (Sus scrofa)

POLL [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

XP_011537953.1, XP_006717840.1, NP_037406.1, NP_001167555.1, NP_001167556.1, NP_001295311.1

OpenTargets

ENSG00000166169

ZINC - Substances

DPOLL_HUMAN

GeneCards

Q9UGP5

HPA

ENSG00000166169-POLL

ZINC target

Q9UGP5

Ensembl

ENSP00000359181, ENST00000299206, ENSP00000485885, ENSG00000166169, ENST00000628479, ENST00000370162, ENSP00000299206, ENST00000370169, ENSP00000359188

PRO

Q9UGP5

Pharos - Targets

Q9UGP5

HMDB Protein

HMDBP00955

PDB

7M0B, 8U0O, 7M43, 7M0C, 7M4L, 5CHG, 7M4C, 7M44, 7M0D, 5IIK, 7M4D, 7M45, 7M0E, 5IIL, 7M4E, 7M46, 3C5G, 5CR0, 1XSP, 7M47, 2BCV, 7M4F, 3MDC, 2PFP, 1XSN, 5CB1, 2PFO, 7M48, 4XQ8, 7M4G, 7UN7, 1XSL, 7M49, 3PMN, 7M4I, 3UQ2, 2BCU, 7M4H, 3UQ0, 4K4H, 7M4J, 3MGH, 7M4A, 4K4G, 3UPQ, 2BCQ, 7M4K, 5CA7, 7M4B, 5DKW, 5III, 2JW5, 5IIJ, 4XUS, 3PNC, 4FO6, 5DDM, 2PFQ, 1RZT, 3C5F, 7M07, 5CJ7, 3HWT, 3HX0, 5CP2, 4XA5, 5IIM, 5CWR, 7M08, 5IIN, 1NZP, 5DDY, 3MDA, 5IIO, 5W4G, 7M09, 2PFN, 2BCS, 2GWS, 3PML, 4K4I, 4XRH, 4X5V, 2BCR, 7M0A, 3HW8, 3MGI

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14191 WRN	2	monoSUMO1-K356,K496,K898-WRN [nucleoplasm] (R-HSA-4568904) WRN [nucleoplasm] (R-HSA-67387)	0.508	2
UniProt:Q08945 SSRP1	1	SSRP1 [nucleoplasm] (R-HSA-65105)	0.508	2
UniProt:Q9Y5B9 SUPT16H	1	SUPT16H [nucleoplasm] (R-HSA-112415)	0.508	2
UniProt:P27694 RPA1	2	polySUMO2,3-K449,K577-RPA1 [nucleoplasm] (R-HSA-4551644) RPA1 [nucleoplasm] (R-HSA-68461)	0.508	2