ATM, activated in response to DNA damage in the form of double strand breaks, phosphorylates ABL1 (c-ABL) on serine residue S456, resulting in the activation of kinase activity of ABL1 (Baskaran et al. 1997).
Baskaran, R, Wood, LD, Whitaker, LL, Canman, CE, Morgan, SE, Xu, Y, Barlow, C, Baltimore, D, Wynshaw-Boris, A, Kastan, MB, Wang, JY
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