SPIDR binds BLM:TOP3A:RMI1:RMI2

Stable Identifier
R-HSA-5686398
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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SPIDR binds the BTRR complex (BLM:TOP3A:RMI1:RMI2) through a direct interaction with BLM. SPIDR also interacts with RAD51, thereby connecting the BTRR complex with Holliday Junctions (Wan et al. 2013).

Literature References
PubMed ID Title Journal Year
23509288 Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair

Wan, L, Han, J, Liu, T, Dong, S, Xie, F, Chen, H, Huang, J

Proc. Natl. Acad. Sci. U.S.A. 2013
Participants
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Orthologous Events
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Created