Reactome | PALM-C100-CKAP4 [plasma membrane]

PALM-C100-CKAP4 [plasma membrane]

Stable Identifier

R-HSA-5686280

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Cytoskeleton-associated protein 4, CKAP4_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q92633 LPAR1

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External Reference Information

External Reference

UniProt:Q07065 CKAP4

Gene Names

CKAP4

Chain

chain:1-602

Reference Genes

BioGPS Gene:10970 CKAP4

COSMIC (genes):CKAP4 CKAP4

CTD Gene:10970 CKAP4

dbSNP Gene:10970 CKAP4

ENSEMBL:ENSG00000136026 CKAP4

ENSEMBL_homo_sapiens_GENE:ENSG00000136026.14 CKAP4

HGNC:16991 CKAP4

KEGG Gene (Homo sapiens):10970 CKAP4

Monarch:10970 CKAP4

NCBI Gene:10970 CKAP4

OMIM:618595 CKAP4

UCSC:Q07065 CKAP4

Reference Transcript

RefSeq:NM_006825.3 CKAP4

Other Identifiers

10970

11726583_s_at

11746889_a_at

16769585

200998_PM_s_at

200998_s_at

200999_PM_s_at

200999_s_at

32529_at

3469686

3469688

3469689

3469690

3469691

3469692

3469693

3469694

3469704

3469705

3469706

3469707

3469708

3469709

3469710

3469711

7966035

A_23_P48056

GE59965

GO:0003723

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005764

GO:0005773

GO:0005783

GO:0005788

GO:0005789

GO:0005791

GO:0005811

GO:0005856

GO:0005886

GO:0016020

GO:0031410

GO:0035577

GO:0035579

GO:0042599

GO:0043226

GO:0048471

GO:0070062

HMNXSV003030067

Hs.74368.0.A1_3p_a_at

PH_hs_0004243

TC12001917.hg

TC12003061.hg

TC12003062.hg

X69910_at

g5803112_3p_a_at

Participates

as an output of

ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Homo sapiens)

as a component of

PALM-C100-CKAP4:SFTPAs [plasma membrane] (Homo sapiens)

as an input of

PALM-C100-CKAP4 binds SFTPAs (Homo sapiens)

Other forms of this molecule

CKAP4 [endoplasmic reticulum lumen]

p-CKAP4 [endoplasmic reticulum lumen]

CKAP4 [azurophil granule membrane]

CKAP4 [plasma membrane]

CKAP4 [specific granule membrane]

PALM-C100-CKAP4 [lamellar body]

Inferred To

ckap4 [plasma membrane] (Danio rerio)

ckap4 [plasma membrane] (Xenopus tropicalis)

CKAP4 [plasma membrane] (Bos taurus)

CKAP4 [plasma membrane] (Canis familiaris)

CKAP4 [plasma membrane] (Sus scrofa)

Ckap4 [plasma membrane] (Mus musculus)

Ckap4 [plasma membrane] (Rattus norvegicus)

PALM-C100-CKAP4 [plasma membrane] (Gallus gallus)

Modified Residues

Name

S-palmitoyl-L-cysteine (palmitoyl group) at 100

Coordinate

100

Modification

palmitoyl group

PsiMod Name

S-palmitoyl-L-cysteine [MOD:00115]

PsiMod Definition

A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.

Cross References

RefSeq

NP_006816.2

OpenTargets

ENSG00000136026

HPA

ENSG00000136026-CKAP4

GeneCards

Q07065

Ensembl

ENSP00000367265, ENST00000378026, ENSG00000136026

PRO

Q07065

Pharos - Targets

Q07065

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NVF7 FBX28			0.643	6
UniProt:P50876 RNF144A	1	RNF144A [endosome membrane] (R-HSA-8938771)	0.589	2
UniProt:P27824 CANX	2	CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.569	3
UniProt:Q92633 LPAR1	1	LPAR1 [plasma membrane] (R-HSA-419354)	0.527	3
UniProt:O95274 LYPD3	2	cleaved GPI-LYPD3 [extracellular region] (R-HSA-8941013) GPI-LYPD3 [plasma membrane] (R-HSA-8940752)	0.527	3
UniProt:Q7LGA3 HS2ST1	1	HS2ST1 [Golgi membrane] (R-HSA-2076393)	0.527	3
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	2
UniProt:Q9H8X2 IPPK	2	IPPK [cytosol] (R-HSA-1604598) IPPK [nucleoplasm] (R-HSA-2023949)	0.527	2
UniProt:O75326 SEMA7A	1	SEMA7A [plasma membrane] (R-HSA-198229)	0.527	2
UniProt:P08842 STS	3	STS [endoplasmic reticulum lumen] (R-HSA-1614318) OxA-STS [endoplasmic reticulum lumen] (R-HSA-1614333) OxA-STS [endoplasmic reticulum membrane] (R-HSA-1606833)	0.527	2
UniProt:Q9UGM1 CHRNA9	1	CHRNA9 [plasma membrane] (R-HSA-507827)	0.527	2
UniProt:Q9Y6Z7 COLEC10	1	COLEC10 [extracellular region] (R-HSA-8852492)	0.527	2
UniProt:Q9P0L0 VAPA	4	VAPA [endoplasmic reticulum membrane] (R-HSA-429677) VAPA [azurophil granule membrane] (R-HSA-6799364) VAPA [plasma membrane] (R-HSA-6806269) VAPA [cytosol] (R-HSA-9609920)	0.527	3
UniProt:Q9BZR6 RTN4R	1	RTN4R [plasma membrane] (R-HSA-194479)	0.527	2
UniProt:P51888 PRELP	11	PRELP [lysosomal lumen] (R-HSA-2105006) KS(2)-PRELP [lysosomal lumen] (R-HSA-2046286) KS(2)-PRELP [extracellular region] (R-HSA-2046162) KS(2)-PRELP [Golgi lumen] (R-HSA-2046160) KS(1)-PRELP [Golgi lumen] (R-HSA-2046258) Keratan(4)-PRELP [Golgi lumen] (R-HSA-2046276) Keratan(3)-PRELP [Golgi lumen] (R-HSA-2046159) Keratan(2)-PRELP [Golgi lumen] (R-HSA-2046219) Keratan(1)-PRELP [Golgi lumen] (R-HSA-2046292) Gal-glycan PRELP [Golgi lumen] (R-HSA-2046279) N-glycan PRELP [Golgi lumen] (R-HSA-2046156)	0.527	3
UniProt:O94766 B3GAT3	2	B3GAT3 R277Q [Golgi membrane] (R-HSA-3621732) B3GAT3 [Golgi membrane] (R-HSA-1889987)	0.527	4
UniProt:Q13503 MED21	1	MED21 [nucleoplasm] (R-HSA-212456)	0.527	2
UniProt:Q5BJH7 YIF1B			0.499	2
UniProt:P04578-PRO_0000038428 ENV			0.462	2
UniProt:P04578 env	7	Surface protein gp120 (P04578) [cytosol] (R-HIV-189269) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211)	0.462	4

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