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GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates
Stable Identifier
R-HSA-5686074
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor signalling cascade (Homo sapiens)
Signal attenuation (Homo sapiens)
GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Homo sapiens)
General
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p-Y427-SHC1 dissociates from GRB2-1:p-4S-SOS1
Literature References
PubMed ID
Title
Journal
Year
7739560
Insulin-stimulated disassociation of the SOS-Grb2 complex.
Pessin, JE
,
Yamauchi, K
,
Waters, SB
Mol Cell Biol
1995
Participants
Input
GRB2-1:p-4S-SOS1:p-Y427-SHC1 [cytosol]
(Homo sapiens)
Output
GRB2-1:p-4S-SOS1 [cytosol]
(Homo sapiens)
p-Y427-SHC1 [cytosol]
(Homo sapiens)
Participates
as an event of
Signal attenuation (Homo sapiens)
Orthologous Events
GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Bos taurus)
GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Canis familiaris)
GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Drosophila melanogaster)
GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Gallus gallus)
GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Mus musculus)
GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Rattus norvegicus)
GRB2-1:p-4S-SOS1:p-Y427-SHC1 dissociates (Sus scrofa)
Created
Jupe, S (2015-03-31)
© 2024
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