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PGA4 [multivesicular body lumen]
Stable Identifier
R-HSA-5685891
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
multivesicular body lumen
Synonyms
Pepsin A-4 ecNumber3.4.23.1/ecNumber, PEPA4_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Homo sapiens)
NAPSA, CTSH, PGA3-5 [multivesicular body lumen] (Homo sapiens)
PGA4 [multivesicular body lumen] (Homo sapiens)
NAPSA, CTSH, PGA3-5 cleave pro-SFTPC (Homo sapiens)
NAPSA, CTSH, PGA3-5 [multivesicular body lumen] (Homo sapiens)
PGA4 [multivesicular body lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P0DJD7 PGA4
Gene Names
PGA4
Chain
signal peptide:1-15, propeptide:16-62, chain:63-388
Reference Genes
BioGPS Gene:643847 PGA4
COSMIC (genes):PGA4 PGA4
CTD Gene:643847 PGA4
dbSNP Gene:643847 PGA4
ENSEMBL:ENSG00000229183 PGA4
ENSEMBL_homo_sapiens_GENE:ENSG00000229183.10 PGA4
HGNC:8886 PGA4
KEGG Gene (Homo sapiens):643847 PGA4
Monarch:643847 PGA4
NCBI Gene:643847 PGA4
OMIM:169700 PGA4
OMIM:169720 PGA4
UCSC:P0DJD7 PGA4
Reference Transcript
RefSeq:XM_016999481.1 PGA4
RefSeq:NM_001079808.3 PGA4
Other Identifiers
11715560_s_at
124906959
128966586
16725511
213265_PM_at
213265_at
3332782
3332783
3332785
3332786
3332788
3332791
3332796
3332797
3332798
3332800
3332801
3332802
3332803
3332804
3332806
3332807
3332809
3332811
3332814
3332815
3332816
3332817
3332818
3332819
3332820
3332821
3332823
3332824
3332825
3332828
3332830
36642_at
643847
7940421
7940431
7940441
A_23_P150547
A_23_P150549
GE60488
GO:0003824
GO:0004190
GO:0005515
GO:0005576
GO:0005615
GO:0005768
GO:0006508
GO:0007586
GO:0008233
GO:0016787
GO:0031410
GO:0043226
GO:0070062
GO:0097486
GO:0140096
HMNXSV003043496
Hs.182183.1.A1_3p_at
ILMN_1677711
ILMN_1687842
ILMN_1727539
ILMN_2232630
J00287_at
TC11000527.hg
TC11003453.hg
TC11003454.hg
Participates
as a member of
NAPSA, CTSH, PGA3-5 [multivesicular body lumen] (Homo sapiens)
Inferred To
ctsD [multivesicular body lumen]
(Dictyostelium discoideum)
PGA5 [multivesicular body lumen]
(Bos taurus)
Dmel\CG5860 [multivesicular body lumen]
(Drosophila melanogaster)
PGA [multivesicular body lumen]
(Canis familiaris)
PGA [multivesicular body lumen]
(Sus scrofa)
pga4 [multivesicular body lumen]
(Xenopus tropicalis)
PGA3 [multivesicular body lumen]
(Gallus gallus)
Cross References
RefSeq
NP_001073276.1
,
XP_016854970.1
OpenTargets
ENSG00000229183
IntEnz
3.4.23.1
GeneCards
P0DJD7
HPA
ENSG00000229183-PGA4
Ensembl
ENST00000378149
,
ENSP00000367391
,
ENSG00000229183
PRO
P0DJD7
Pharos - Targets
P0DJD7
PDB
1FLH
,
1QRP
,
3UTL
,
1PSO
,
1PSN
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15151 PVR
1
PVR [plasma membrane]
(R-HSA-420600)
0.556
3
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