Reactome | PPP6R1 [cytosol]

PPP6R1 [cytosol]

Stable Identifier

R-HSA-5685721

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        PP6 dephosphorylates SEC24 (Homo sapiens)
        
        PP6 [cytosol] (Homo sapiens)
        
        PPP6R1,3 [cytosol] (Homo sapiens)
        
        PPP6R1 [cytosol] (Homo sapiens)

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - ER to Golgi Anterograde Transport (Homo sapiens)
    - COPII-mediated vesicle transport (Homo sapiens)
      - PP6 dephosphorylates SEC24 (Homo sapiens)
        
        PP6 [cytosol] (Homo sapiens)
        
        PPP6R1,3 [cytosol] (Homo sapiens)
        
        PPP6R1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UPN7 PPP6R1

Gene Names

PPP6R1, KIAA1115, PP6R1, SAPS1

Chain

chain:1-881

Reference Genes

BioGPS Gene:22870 PPP6R1

COSMIC (genes):PPP6R1 PPP6R1

CTD Gene:22870 PPP6R1

dbSNP Gene:22870 PPP6R1

ENSEMBL:ENSG00000105063 PPP6R1

ENSEMBL_homo_sapiens_GENE:ENSG00000105063 PPP6R1

HGNC:29195 PPP6R1

KEGG Gene (Homo sapiens):22870 PPP6R1

Monarch:22870 PPP6R1

NCBI Gene:22870 PPP6R1

OMIM:610875 PPP6R1

UCSC:Q9UPN7 PPP6R1

Reference Transcript

RefSeq:NM_014931.3 PPP6R1

Other Identifiers

0001740739

11718431_x_at

11747158_a_at

16875683

209229_s_at

22870

36862_at

3871258

3871259

3871260

3871261

3871262

3871263

3871264

3871265

3871266

3871267

3871274

3871275

3871277

3871278

3871279

3871280

3871281

3871283

3871284

3871285

3871286

3871288

3871290

3871291

3871292

3871293

3871296

3871297

3871300

3871301

43989

63681

8039413

A_23_P119448

AAH02799

AAH68014

AAH94753

BAA83067

CCDS46186

ENSG00000105063

ENSP00000414202

ENSP00000467521

ENST00000412770

ENST00000587283

EntrezGene:22870

g12803904_3p_a_at

GE81976

GO:0000139

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005794

GO:0005829

GO:0006464

GO:0006810

GO:0008150

GO:0016192

GO:0017048

GO:0019899

GO:0019903

GO:0022607

GO:0043226

GO:0043666

GO:0048208

GO:0061024

GO:0065003

HGNC:29195

HPA043989

HPA063681

ILMN_1794085

IPR007587

IPR016024

MIM:610875

NM_014931

NP_055746

PF04499

PH_hs_0024883

PPP6R1

PPP6R1-201

PPP6R1-203

TC19001864.hg

uc002qjw.5

uc061cyp.1

UPI0000202C6D

Participant Of

hasMember

PPP6R1,3 [cytosol]

Inferred To

Homologues of PPP6R1 [cytosol] (Bos taurus)

Homologues of PPP6R1 [cytosol] (Canis familiaris)

Homologues of PPP6R1 [cytosol] (Rattus norvegicus)

PPP6R1 [cytosol] (Bos taurus)

PPP6R1 [cytosol] (Canis familiaris)

PPP6R1 [cytosol] (Mus musculus)

PPP6R1 [cytosol] (Rattus norvegicus)

PPP6R1 [cytosol] (Sus scrofa)

PPP6R1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_055746.3

OpenTargets

ENSG00000105063

GeneCards

Q9UPN7

PRO

Q9UPN7

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11142 HSPA8	8	HSPA8 [cytosol] (R-HSA-264476) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [nucleoplasm] (R-HSA-5082380)	0.462	2