Members of the signaling lymphocytic-activation molecule (SLAM) family, are all encoded in the SLAM locus, and are mostly homotypic self-associating receptors expressed by cells of hemopoietic origin (Veillette et al. 2006). SLAMF6 (also called as NTB-A) is a homophilic receptor that stimulates cytotoxicity in natural killer (NK) cells, regulates bactericidal activities in neutrophils, and potentiates T helper 2 (Th2) responses (Cao et al. 2006).
Griewank, K, Borowski, C, Rietdijk, S, Wang, N, Julien, A, Wei, DG, Mamchak, AA, Terhorst, C, Bendelac, A
Cao, E, Ramagopal, UA, Fedorov, A, Fedorov, E, Yan, Q, Lary, JW, Cole, JL, Nathenson, SG, Almo, SC
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