BCDX2 complex formation

Stable Identifier
R-HSA-5685318
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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BCDX2 complex formation
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RAD51 paralogs RAD51B, RAD51C, RAD51D and XRCC2 form a complex named BCDX2 with 1:1:1:1 stoichiometry. In this complex, RAD51B directly interacts with RAD51C, which interacts with RAD51D, which interacts with XRCC2 (Masson et al. 2001, Chun et al. 2013).

Literature References
PubMed ID Title Journal Year
11751635 Identification and purification of two distinct complexes containing the five RAD51 paralogs

Masson, JY, Tarsounas, MC, Stasiak, AZ, Stasiak, A, Shah, R, McIlwraith, MJ, Benson, FE, West, SC

Genes Dev. 2001
23149936 Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway

Chun, J, Buechelmaier, ES, Powell, SN

Mol. Cell. Biol. 2013
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
BCDX2 complex formation (Bos taurus)
BCDX2 complex formation (Canis familiaris)
BCDX2 complex formation (Danio rerio)
BCDX2 complex formation (Gallus gallus)
BCDX2 complex formation (Mus musculus)
BCDX2 complex formation (Rattus norvegicus)
BCDX2 complex formation (Sus scrofa)
Authored
Orlic-Milacic, M  (2015-05-12)
Reviewed
Borowiec, JA  (2015-06-12)
Created
Orlic-Milacic, M  (2015-03-27)