Reactome | SFTPD [endoplasmic reticulum membrane]

SFTPD [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-5685278

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Pulmonary surfactant-associated protein D (SP-D), SFTPD_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P35247 SFTPD

Gene Names

SFTPD, COLEC7, PSPD, SFTP4

Chain

signal peptide:1-20, chain:21-375

Reference Genes

COSMIC (genes):SFTPD SFTPD

dbSNP Gene:6441 SFTPD

ENSEMBL:ENSG00000133661 SFTPD

Participates

as a component of

SFTPD trimer [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

SFTPD [clathrin-coated endocytic vesicle]

SFTPD [extracellular region]

Inferred To

hbl4 [endoplasmic reticulum membrane] (Danio rerio)

SFTPD [endoplasmic reticulum membrane] (Bos taurus)

SFTPD [endoplasmic reticulum membrane] (Canis familiaris)

SFTPD [endoplasmic reticulum membrane] (Plasmodium falciparum)

SFTPD [endoplasmic reticulum membrane] (Sus scrofa)

Sftpd [endoplasmic reticulum membrane] (Mus musculus)

Sftpd [endoplasmic reticulum membrane] (Rattus norvegicus)

mbl2 [endoplasmic reticulum membrane] (Danio rerio)

Homologues of SFTPD [endoplasmic reticulum membrane] (Danio rerio)

Homologues of SFTPD [endoplasmic reticulum membrane] (Sus scrofa)

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) complex N-glycan-PALM-Spike S1 Fragment [virion membrane] (R-COV-9694638) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) fully glycosylated Spike [virion membrane] (R-COV-9698327) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997)	0.544	3

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