Surfactant proteins B (SFTPB) is a small hydrophobic surfactant protein that maintains surface tension in alveoli. In the nucleus, SFTPB is regulated by a key factor, transcription termination factor 1 (TTF1), bound to thyroid transcription factor 1-associated protein 26 (CCDC59 aka TAP26, BR22), to enhance TTF1-transactivated SFTPB promoter activity (Whitsett & Glasser 1998, Yang et al. 2006).
Guo, Y, Weissler, JC, Yang, YS, Yang, MC, Liu, CC
Glasser, SW, Whitsett, JA
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