Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
|Nat Cell Biol
Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response
|Mol Biol Cell
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling
Rapid PIKK-Dependent Release of Chk1 from Chromatin Promotes the DNA-Damage Checkpoint Response
Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.
Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress
|Nucleic Acids Res.
Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress
|J. Biol. Chem.
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
|Mol Cell Biol
ATR, Claspin and the Rad9-Rad1-Hus1 complex regulate Chk1 and Cdc25A in the absence of DNA damage