Reactome | PDPN [plasma membrane]

PDPN [plasma membrane]

Stable Identifier

R-HSA-5684794

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Podoplanin, PDPN_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q86YL7 PDPN

Gene Names

PDPN, GP36, PSEC0003, PSEC0025

Chain

signal peptide:1-22, chain:23-162, peptide:151-162

Reference Genes

BioGPS Gene:10630 PDPN

COSMIC (genes):PDPN PDPN

CTD Gene:10630 PDPN

dbSNP Gene:10630 PDPN

ENSEMBL:ENSG00000162493 PDPN

HGNC:29602 PDPN

KEGG:hsa:10630 PDPN

Monarch:10630 PDPN

NCBI Gene:10630 PDPN

OMIM:608863 PDPN

UCSC:Q86YL7 PDPN

Reference Transcript

Other Identifiers

10630

11724735_a_at

11724736_x_at

11724737_a_at

16659459

204879_PM_at

204879_at

221898_PM_at

221898_at

226658_PM_at

226658_at

2321194

2321195

2321196

2321197

2321198

2321199

2321203

2321204

2321206

2321209

2321214

2321215

41870_at

41871_at

51715_at

7898057

A_14_P130035

A_23_P430068

GO:0001726

GO:0001946

GO:0005102

GO:0005515

GO:0005737

GO:0005739

GO:0005829

GO:0005886

GO:0007155

GO:0007165

GO:0007266

GO:0008285

GO:0008360

GO:0010718

GO:0016020

GO:0016323

GO:0016324

GO:0016477

GO:0019956

GO:0030027

GO:0030054

GO:0030168

GO:0030175

GO:0030324

GO:0030335

GO:0031258

GO:0031410

GO:0031527

GO:0031528

GO:0032587

GO:0042995

GO:0043066

GO:0043226

GO:0044319

GO:0045121

GO:0048535

GO:0048856

GO:0048870

GO:0051087

GO:0060838

GO:0061851

GO:0070161

GO:0070252

GO:0090091

GO:0097197

GO:1900024

GO:1901731

GO:1904328

GO:2000392

HMNXSV003000273

Hs.135150.2.A1_3p_at

Hs.135150.2.A2_3p_at

ILMN_1670490

ILMN_2404903

PH_hs_0033987

TC01000181.hg

g5454097_3p_a_at

Participates

as an output of

Expression of PDPN in primordial germ cells (Homo sapiens)

as an input of

CLEC1B dimer binds PDPN (Homo sapiens)

as a component of

Inferred To

bovAggrus [plasma membrane] (Bos taurus)

Pdpn [plasma membrane] (Mus musculus)

Pdpn [plasma membrane] (Rattus norvegicus)

PDPN [plasma membrane] (Canis familiaris)

PDPN [plasma membrane] (Gallus gallus)

PDPN [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_938203.2, NP_001006626.1, NP_006465.3, NP_001006625.1, XP_006710358.1

OpenTargets

ENSG00000162493

ENSEMBL

ENSP00000478125, ENST00000294489, ENST00000487038, ENST00000621990, ENSP00000427537, ENSP00000425304, ENSP00000365225, ENST00000376057, ENST00000376061, ENSP00000365229, ENSP00000294489, ENST00000475043, ENSP00000426063, ENST00000513143

HPA

ENSG00000162493-PDPN

PRO

Q86YL7

Pharos - Targets

Q86YL7

GlyGen

Q86YL7

PDB

3WSR, 7CQD, 7CQC, 7C94, 5XCV, 4YO0

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9P126-1 CLEC1B			0.558	2
UniProt:Q9NUH8 TM14B			0.556	3