NBN binds KPNA2

Stable Identifier
R-HSA-5684008
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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NBN binds KPNA2
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In the cytosol, NBN (NBS1) binds KPNA2, an importin alpha family member. The armadillo repeats of KPNA2 and a nuclear localization signal (NLS) of NBN are involved in the interaction (Tseng et al. 2005).

Literature References
PubMed ID Title Journal Year
16188882 Importin KPNA2 is required for proper nuclear localization and multiple functions of NBS1

Wu, KJ, Chang, CY, Teng, SC, Tseng, SF

J. Biol. Chem. 2005
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Orthologous Events
NBN binds KPNA2 (Bos taurus)
NBN binds KPNA2 (Canis familiaris)
NBN binds KPNA2 (Danio rerio)
NBN binds KPNA2 (Drosophila melanogaster)
NBN binds KPNA2 (Gallus gallus)
NBN binds KPNA2 (Mus musculus)
NBN binds KPNA2 (Rattus norvegicus)
NBN binds KPNA2 (Sus scrofa)
NBN binds KPNA2 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2015-05-12)
Reviewed
Borowiec, JA  (2015-06-12)
Created
Orlic-Milacic, M  (2015-03-17)
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