Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
p-Y142-H2AFX-Nucleosome [nucleoplasm]
Stable Identifier
R-HSA-5683932
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Nucleosome with histone H2AFX phosphorylated at tyrosine Y142
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
DNA Double Strand Break Response (Homo sapiens)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Homo sapiens)
ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Homo sapiens)
DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Homo sapiens)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Homo sapiens)
ATM recognizes H2AFX-Nucleosomes (Homo sapiens)
DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Homo sapiens)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Homo sapiens)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Homo sapiens)
WICH phosphorylates H2AFX on Y142 (Homo sapiens)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Homo sapiens)
Participants
components
x 2
HIST1H4 [nucleoplasm]
(Homo sapiens)
x 2
HIST3H3 [nucleoplasm]
(Homo sapiens)
x 2
Histone H2B [nucleoplasm]
(Homo sapiens)
x 2
p-Y143-H2AFX [nucleoplasm]
(Homo sapiens)
Participates
as a component of
DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Homo sapiens)
as an input of
ATM recognizes H2AFX-Nucleosomes (Homo sapiens)
as an output of
WICH phosphorylates H2AFX on Y142 (Homo sapiens)
Inferred To
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Bos taurus)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Canis familiaris)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Danio rerio)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Dictyostelium discoideum)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Drosophila melanogaster)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Gallus gallus)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Mus musculus)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Plasmodium falciparum)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Rattus norvegicus)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Saccharomyces cerevisiae)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Schizosaccharomyces pombe)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Sus scrofa)
p-Y142-H2AFX-Nucleosome [nucleoplasm]
(Xenopus tropicalis)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text