SFTPC gene produces pro-SFTPC protein

Stable Identifier
R-HSA-5683836
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, endoplasmic reticulum membrane
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SFTPC gene produces pro-SFTPC protein
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The human gene SFTPC produces surfactant protein C (SFTPC) (Whitsett & Glasser 1998, Kelly et al. 1996). The transcription complex transcription termination factor 1 and thyroid transcription factor 1-associated protein 26 (TTF1:CCDC59), enhances TTF1-transactivated SFTPC promoter activity.

Literature References
PubMed ID Title Journal Year
9813380 Regulation of surfactant protein gene transcription

Glasser, SW, Whitsett, JA

Biochim. Biophys. Acta 1998
8636114 Transcription of the lung-specific surfactant protein C gene is mediated by thyroid transcription factor 1

Bachurski, CJ, Kelly, SE, Burhans, MS, Glasser, SW

J. Biol. Chem. 1996
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
CCDC59:TTF1:SFTPC gene [nucleoplasm] (Homo sapiens)
Authored
Jassal, B  (2015-03-17)
Reviewed
D'Eustachio, P  (2015-08-17)
Created
Jassal, B  (2015-03-17)
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