SFTPC gene produces pro-SFTPC protein

Stable Identifier
R-HSA-5683836
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, endoplasmic reticulum membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SFTPC gene produces pro-SFTPC protein
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The human gene SFTPC produces surfactant protein C (SFTPC) (Whitsett & Glasser 1998, Kelly et al. 1996). The transcription complex transcription termination factor 1 and thyroid transcription factor 1-associated protein 26 (TTF1:CCDC59), enhances TTF1-transactivated SFTPC promoter activity.
Literature References
PubMed ID Title Journal Year
9813380 Regulation of surfactant protein gene transcription

Glasser, SW, Whitsett, JA

Biochim. Biophys. Acta 1998
8636114 Transcription of the lung-specific surfactant protein C gene is mediated by thyroid transcription factor 1

Bachurski, CJ, Kelly, SE, Burhans, MS, Glasser, SW

J. Biol. Chem. 1996
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
CCDC59:TTF1:SFTPC gene [nucleoplasm] (Homo sapiens)
Authored
Jassal, B  (2015-03-17)
Reviewed
D'Eustachio, P  (2015-08-17)
Created
Jassal, B  (2015-03-17)
Cite Us!