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TRAPPC2 [cytosol]
Stable Identifier
R-HSA-5683757
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SEDL, TRAPP1, TRAPP2, TRAPP3, TRAPP core
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
TRAPPC complexes exchange GTP for GDP on RAB1 (Homo sapiens)
TRAPPCs [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
TRAPPCIII [cytosol] (Homo sapiens)
TRAPPC2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P0DI81 TRAPPC2
Gene Names
TRAPPC2, SEDL
Chain
chain:1-140
Reference Genes
BioGPS Gene:6399 TRAPPC2
COSMIC (genes):TRAPPC2 TRAPPC2
CTD Gene:6399 TRAPPC2
dbSNP Gene:6399 TRAPPC2
ENSEMBL:ENSG00000196459 TRAPPC2
HGNC:23068 TRAPPC2
KEGG:hsa:6399 TRAPPC2
Monarch:6399 TRAPPC2
NCBI Gene:6399 TRAPPC2
OMIM:300202 TRAPPC2
UCSC:P0DI81 TRAPPC2
Reference Transcript
RefSeq:XM_054327564.1 TRAPPC2
RefSeq:XM_047442352.1 TRAPPC2
RefSeq:NM_001011658.4 TRAPPC2
RefSeq:XM_047442351.1 TRAPPC2
RefSeq:NM_014563.6 TRAPPC2
RefSeq:NM_001128835.3 TRAPPC2
RefSeq:XM_011545566.3 TRAPPC2
RefSeq:XM_054327565.1 TRAPPC2
RefSeq:XM_011545565.1 TRAPPC2
Participates
as a component of
TRAPPCIII [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
Inferred To
Trappc2 [cytosol]
(Mus musculus)
Trappc2 [cytosol]
(Rattus norvegicus)
Trs20 [cytosol]
(Drosophila melanogaster)
trs20 [cytosol]
(Schizosaccharomyces pombe)
TRS20 [cytosol]
(Saccharomyces cerevisiae)
TRAPPC2 [cytosol]
(Bos taurus)
TRAPPC2 [cytosol]
(Canis familiaris)
TRAPPC2 [cytosol]
(Gallus gallus)
TRAPPC2 [cytosol]
(Plasmodium falciparum)
TRAPPC2 [cytosol]
(Sus scrofa)
sedl-1 [cytosol]
(Caenorhabditis elegans)
trappc2 [cytosol]
(Danio rerio)
trappc2 [cytosol]
(Dictyostelium discoideum)
Ghost homologue of TRAPPC2 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
XP_011543868.1
,
XP_011543867.1
,
NP_001122307.2
,
XP_054183539.1
,
NP_055378.1
,
NP_001011658.1
,
XP_047298307.1
,
XP_054183540.1
,
XP_047298308.1
OpenTargets
ENSG00000196459
ENSEMBL
ENST00000683983
,
ENST00000359680
,
ENSG00000196459
,
ENST00000518847
,
ENST00000683569
,
ENSP00000428900
,
ENST00000458511
,
ENSP00000508155
,
ENSP00000352708
,
ENSP00000507474
,
ENSP00000392495
,
ENST00000380579
,
ENSP00000369953
HPA
ENSG00000196459-TRAPPC2
GeneCards
TRAPPC2
PRO
P0DI81
Pharos - Targets
P0DI81
Orphanet
TRAPPC2
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.558
3
UniProt:Q9UBC2 EPS15L1
2
EPS15L1 [plasma membrane]
(R-HSA-182937)
EPS15L1 [cytosol]
(R-HSA-8935900)
0.556
3
UniProt:Q719H9 KCTD1
1
KCTD1 [nucleoplasm]
(R-HSA-8864339)
0.556
3
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