ATG7:ATG3:LC3 dissociates

Stable Identifier
R-HSA-5683593
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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ATG7 dissociates from the ATG3-LC3 conjugate (Tanida et al. 2012, Klionsky & Schulman 2014).
Literature References
PubMed ID Title Journal Year
22170151 The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation

Tanida, I, Komatsu, M, Yamasaki, M, Ueno, T

Autophagy 2012
11825910 Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

Tanida, I, Tanida-Miyake, E, Komatsu, M, Kominami, E, Ueno, T

J. Biol. Chem. 2002
24747438 Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3

Nath, S, Shteyn, V, Yamamoto, A, Melia, TJ, Dancourt, J, Bewersdorf, J, Nag, S, Puente, G, Antonny, B, Fong, WM

Nat. Cell Biol. 2014
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