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K48PolyUb-KDM4B [nucleoplasm]
Stable Identifier
R-HSA-5683074
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
K48PolyUb-JMJD2B
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
DNA Double Strand Break Response (Homo sapiens)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Homo sapiens)
RNF8 and RNF168 ubiquitinate KDM4A,B (Homo sapiens)
K48PolyUb-KDM4A,B [nucleoplasm] (Homo sapiens)
K48PolyUb-KDM4B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O94953 KDM4B
Gene Names
KDM4B, JHDM3B, JMJD2B, KIAA0876
Chain
chain:1-1096
Reference Genes
BioGPS Gene:23030 KDM4B
COSMIC (genes):KDM4B KDM4B
CTD Gene:23030 KDM4B
dbSNP Gene:23030 KDM4B
ENSEMBL:ENSG00000127663 KDM4B
HGNC:29136 KDM4B
KEGG Gene (Homo sapiens):23030 KDM4B
Monarch:23030 KDM4B
NCBI Gene:23030 KDM4B
OMIM:609765 KDM4B
UCSC:O94953 KDM4B
Reference Transcript
RefSeq:NM_015015.2 KDM4B
Other Identifiers
11761992_at
23030
3817734
3817741
3817751
3817752
3817754
3817755
3817756
3817763
3817776
3817780
3817784
3817800
3817801
3817802
3817803
3817804
A_33_P3254101
A_33_P3396600
GE509887
GO:0003674
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0006259
GO:0006302
GO:0006325
GO:0006338
GO:0006464
GO:0006950
GO:0008150
GO:0016491
GO:0032452
GO:0032454
GO:0033169
GO:0034641
GO:0043167
GO:0043226
GO:0046872
GO:0051213
GO:0051276
GO:0051864
GO:0070544
HMNXSV003020264
TC19000100.hg
Participates
as a member of
K48PolyUb-KDM4A,B [nucleoplasm] (Homo sapiens)
Other forms of this molecule
KDM4B [nucleoplasm]
Inferred To
RPH1 [nucleoplasm]
(Saccharomyces cerevisiae)
jmj3 [nucleoplasm]
(Schizosaccharomyces pombe)
kdm4b [nucleoplasm]
(Danio rerio)
Kdm4b [nucleoplasm]
(Mus musculus)
Kdm4b [nucleoplasm]
(Rattus norvegicus)
KDM4B [nucleoplasm]
(Canis familiaris)
KDM4B [nucleoplasm]
(Gallus gallus)
KDM4B [nucleoplasm]
(Sus scrofa)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [nucleoplasm]) at unknown position
Modification
K48polyUb [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_055830.1
Guide to Pharmacology - Targets
2676
OpenTargets
ENSG00000127663
HPA
ENSG00000127663-KDM4B
ZINC - Substances
KDM4B_HUMAN
GeneCards
O94953
ZINC target
O94953
Ensembl
ENSP00000371178
,
ENST00000381759
,
ENSG00000127663
PRO
O94953
Pharos - Targets
O94953
ZINC - Predictions - Purchasable
KDM4B_HUMAN
PDB
4UC4
,
4LXL
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