4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane

Stable Identifier
R-HSA-5682103
Type
Reaction [transition]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane, plasma membrane
ReviewStatus
5/5
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4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane
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Palmitoylation of ATP-binding cassette sub-family A member 1 (ABCA1) at Cys 3, 23, 1110 and 1111 is essential for its proper trafficking from the ER membrane to the plasma membrane where it is essential for the transport of lipids (Singaraja et al. 2009).
Literature References
PubMed ID Title Journal Year
19556522 Palmitoylation of ATP-binding cassette transporter A1 is essential for its trafficking and function

Vaid, K, El-Husseini, Ael D, Sanders, SS, Arstikaitis, P, Hayden, MR, Drisdel, RC, Kang, MH, Singaraja, RR, Berthiaume, L, Green, WN, Vilas, GL, Coutinho, J

Circ. Res. 2009
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Orthologous Events
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Bos taurus)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Caenorhabditis elegans)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Canis familiaris)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Danio rerio)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Dictyostelium discoideum)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Drosophila melanogaster)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Gallus gallus)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Mus musculus)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Plasmodium falciparum)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Rattus norvegicus)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Sus scrofa)
4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Xenopus tropicalis)
Authored
Jassal, B  (2015-03-05)
Reviewed
D'Eustachio, P  (2016-01-15)
Created
Jassal, B  (2015-03-05)
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