ATG10 transfers ATG12 from ATG7 to ATG10

Stable Identifier
R-HSA-5681999
Type
Reaction
Species
Homo sapiens
Compartment
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After activation, ATG12 is transferred to ATG10, which has a function that is analogous to an E2 enzyme (Shintani et al. 1999, Mizushima et al. 2002). ATG12 is transferred to the Cys-166 residue of ATG10 to form a thioester (Nemoto et al. 2003).

Participants
Participates
Catalyst Activity

Atg12 transferase activity of ATG12:ATG7:CysO572-ATG7:ATG10 [cytosol]

Inferred From
Authored
Reviewed
Created
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