LC3 is cleaved by ATG4

Stable Identifier
R-HSA-5681987
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

LC3 family proteins are processed by members of the ATG4 family, which remove a C-terminal residue to create an exposed C-terminal glycine (Kirisako et al. 2000, Tanida et al. 2004, Kabeya et al. 2004, Li et al. 2011). Processed LC3 proteins are sometimes referred to as LC3-I.

Literature References
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
cysteine-type endopeptidase activity of ATG4 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created