Reactome | WDR45B [cytosol]

WDR45B [cytosol]

Stable Identifier

R-HSA-5678303

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

WD repeat domain phosphoinositide-interacting protein 3, WIPI3_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q5MNZ6 WDR45B

Gene Names

WDR45B, WDR45L, WIPI3

Chain

chain:1-344

Reference Genes

BioGPS Gene:56270 WDR45B

COSMIC (genes):WDR45B WDR45B

CTD Gene:56270 WDR45B

dbSNP Gene:56270 WDR45B

ENSEMBL:ENSG00000141580.16 WDR45B

HGNC:25072 WDR45B

KEGG Gene (Homo sapiens):56270 WDR45B

Monarch:56270 WDR45B

NCBI Gene:56270 WDR45B

OMIM:609226 WDR45B

UCSC:Q5MNZ6 WDR45B

Reference Transcript

RefSeq:NM_019613.3 WDR45B

Other Identifiers

0003390685

11715797_a_at

11715798_x_at

11750162_a_at

16850264

209076_PM_s_at

209076_s_at

3752540

3752542

3775156

3775158

3775159

3775160

3775162

3775164

3775168

3775169

3775175

3775176

3775179

3775186

3775187

3775193

3775197

3775198

39185_at

56270

8019523

A_23_P207020

GE54765

GO:0000045

GO:0000407

GO:0000422

GO:0005515

GO:0005622

GO:0005737

GO:0005764

GO:0005773

GO:0005829

GO:0006497

GO:0006914

GO:0007005

GO:0008289

GO:0009267

GO:0019898

GO:0032266

GO:0034045

GO:0034497

GO:0036211

GO:0043226

GO:0044804

GO:0062078

GO:0080025

HMNXSV003020638

ILMN_1685763

ILMN_1719140

PH_hs_0022988

TC17001984.hg

g12803025_3p_a_at

Participates

as a candidate of

WIPI1,WIPI2,(WDR45,WDR45B) [cytosol] (Homo sapiens)

Inferred To

HSV2 [cytosol] (Saccharomyces cerevisiae)

wdr45b [cytosol] (Danio rerio)

wdr45b [cytosol] (Xenopus tropicalis)

Dmel\CG11975 [cytosol] (Drosophila melanogaster)

WDR45B [cytosol] (Bos taurus)

WDR45B [cytosol] (Canis familiaris)

WDR45B [cytosol] (Dictyostelium discoideum)

WDR45B [cytosol] (Gallus gallus)

Wdr45b [cytosol] (Mus musculus)

Wdr45b [cytosol] (Rattus norvegicus)

hsv2 [cytosol] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_062559.2

OpenTargets

ENSG00000141580

GeneCards

Q5MNZ6

HPA

ENSG00000141580-WDR45B

Ensembl

ENSG00000141580, ENSP00000376139, ENST00000392325

PRO

Q5MNZ6

Pharos - Targets

Q5MNZ6

Orphanet

25036

PDB

6IYY, 6KLR

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9697006) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) fully glycosylated Spike [virion membrane] (R-COV-9698327) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791)	0.499	4

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