KCNJ11:ABCC9 transports K+ from extracellular region to cytosol

Stable Identifier
R-HSA-5678261
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, extracellular region, plasma membrane
ReviewStatus
5/5
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KCNJ11:ABCC9 transports K+ from extracellular region to cytosol
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ATP-sensitive inward rectifier potassium channel 11 (KCNJ11) is an inward rectifier potassium channel, favouring potassium flow into the cell rather than out of it. KCNJ11 can complex with ATP-binding cassette sub-family member 9 (ABCC9) to form cardiac and smooth muscle-type K+(ATP) channels. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (Babenko et al. 1998, Tammaro & Ashcroft 2007).
Literature References
Participants
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Output
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as an event of
Catalyst Activity

inward rectifier potassium channel activity of KCNJ11:ABCC9 [plasma membrane]

Physical Entity
KCNJ11:ABCC9 [plasma membrane] (Homo sapiens)
Activity
inward rectifier potassium channel activity (GO:0005242)
Orthologous Events
KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Bos taurus)
KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Canis familiaris)
KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Drosophila melanogaster)
KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Gallus gallus)
KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Mus musculus)
KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Rattus norvegicus)
KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Sus scrofa)
KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Xenopus tropicalis)
Cross References
Rhea
Authored
Jassal, B  (2015-02-23)
Reviewed
Moitra, K  (2015-04-28)
Created
Jassal, B  (2015-02-23)
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