Reactome | Methionine sulfoxide is oxidised to methionine sulfone

Methionine sulfoxide is oxidised to methionine sulfone

Stable Identifier

R-HSA-5676926

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

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Methionine sulfoxide is oxidised to methionine sulfone

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The major oxidation product of protein-bound methionine is methionine sulfoxide. This can be further oxidised to methionine sulfone (Nielsen et al. 1985).

Literature References

PubMed ID	Title	Journal	Year
3933547	Reactions of proteins with oxidizing lipids. 1. Analytical measurements of lipid oxidation and of amino acid losses in a whey protein-methyl linolenate model system Nielsen, HK, Löliger, J, Hurrell, RF	Br. J. Nutr.	1985

Participants

Input

Output

2 x H2O [cytosol]
2 x MetOO [cytosol]

Participant Of

hasEvent

Protein repair

Authored

Jupe, S (2015-01-05)

Reviewed

Meldal, BH (2015-10-05)

Created

Jupe, S (2015-02-20)