Reactome | MSRB2 [cytosol]

MSRB2 [cytosol]

Stable Identifier

R-HSA-5676906

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Methionine-R-sulfoxide reductase B2, mitochondrial, MSRB2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y3D2 MSRB2

Gene Names

MSRB2, CBS-1, MSRB, CGI-131

Chain

transit peptide:1-20, chain:21-182

Reference Genes

BioGPS Gene:22921 MSRB2

COSMIC (genes):MSRB2 MSRB2

CTD Gene:22921 MSRB2

dbSNP Gene:22921 MSRB2

ENSEMBL:ENSG00000148450 MSRB2

ENSEMBL_homo_sapiens_GENE:ENSG00000148450.13 MSRB2

HGNC:17061 MSRB2

KEGG Gene (Homo sapiens):22921 MSRB2

Monarch:22921 MSRB2

NCBI Gene:22921 MSRB2

OMIM:613782 MSRB2

UCSC:Q9Y3D2 MSRB2

Reference Transcript

RefSeq:NM_012228.3 MSRB2

Other Identifiers

11718996_at

11757405_a_at

16703220

218773_PM_s_at

218773_s_at

219451_PM_at

219451_at

22921

230575_PM_at

230575_at

3238768

3238769

3238770

3238779

3238780

3238783

3238787

3238789

3238790

3238791

3238792

3238793

3238794

3238795

43370_at

56432_at

59315_at

7926661

A_14_P101187

A_23_P97932

A_33_P3278318

GE664105

GO:0003779

GO:0003824

GO:0005515

GO:0005737

GO:0005739

GO:0005829

GO:0006979

GO:0007010

GO:0008092

GO:0008270

GO:0016491

GO:0016671

GO:0030041

GO:0030091

GO:0033743

GO:0033745

GO:0043226

GO:0046872

GO:0065003

HMNXSV003037935

Hs.159204.0.A1_3p_at

ILMN_1657977

PH_hs_0026410

TC10000163.hg

g6912591_3p_s_at

g7706344_3p_at

Participates

as a member of

MSRBs [cytosol] (Homo sapiens)

Inferred To

MSRB2 [cytosol] (Bos taurus)

MSRB2 [cytosol] (Caenorhabditis elegans)

MSRB2 [cytosol] (Canis familiaris)

MSRB2 [cytosol] (Danio rerio)

MSRB2 [cytosol] (Mus musculus)

MSRB2 [cytosol] (Rattus norvegicus)

MSRB2 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_036360.3

OpenTargets

ENSG00000148450

IntEnz

1.8.4.12, 1.8.4.14

GeneCards

Q9Y3D2

HPA

ENSG00000148450-MSRB2

Ensembl

ENST00000376510, ENSG00000148450, ENSP00000365693

PRO

Q9Y3D2

Pharos - Targets

Q9Y3D2

HMDB Protein

HMDBP09182

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3
UniProt:P02649 APOE	10	APOE [early endosome] (R-HSA-2429687) APOE [endosome lumen] (R-HSA-174804) APOE [endosome membrane] (R-HSA-174766) APOE [clathrin-coated endocytic vesicle membrane] (R-HSA-174651) APOE [plasma membrane] (R-HSA-174615) APOE-4 [extracellular region] (R-HSA-9711070) APOE [endocytic vesicle lumen] (R-HSA-3221641) APOE [extracellular region] (R-HSA-174646) p-APOE [endoplasmic reticulum lumen] (R-HSA-8956980) APOE [endoplasmic reticulum lumen] (R-HSA-6784908)	0.556	3
UniProt:P37840 SNCA	5	SNCA A30P [cytosol] (R-HSA-5658569) SNCA [extracellular region] (R-HSA-976954) Ub-SNCA [cytosol] (R-HSA-5660754) p-S129-SNCA [cytosol] (R-HSA-9836432) SNCA [cytosol] (R-HSA-5658500)	0.556	3
UniProt:Q92597 NDRG1	1	NDRG1 [cytosol] (R-HSA-5628834)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	12
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3

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