Reactome | PCMT1 [cytosol]

PCMT1 [cytosol]

Stable Identifier

R-HSA-5676580

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Protein-L-isoaspartate, PIMT_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P22061 PCMT1

Gene Names

PCMT1

Chain

initiator methionine:1, chain:2-227

Reference Genes

BioGPS Gene:5110 PCMT1

COSMIC (genes):PCMT1 PCMT1

CTD Gene:5110 PCMT1

dbSNP Gene:5110 PCMT1

ENSEMBL:ENSG00000120265 PCMT1

HGNC:8728 PCMT1

KEGG:hsa:5110 PCMT1

Monarch:5110 PCMT1

NCBI Gene:5110 PCMT1

OMIM:176851 PCMT1

UCSC:P22061 PCMT1

Reference Transcript

Inferred To

Pcmt1 [cytosol] (Mus musculus)

Pcmt1 [cytosol] (Rattus norvegicus)

PCMT1 [cytosol] (Bos taurus)

PCMT1 [cytosol] (Canis familiaris)

PCMT1 [cytosol] (Gallus gallus)

PCMT1 [cytosol] (Plasmodium falciparum)

PCMT1 [cytosol] (Sus scrofa)

pcmA [cytosol] (Dictyostelium discoideum)

pcmt [cytosol] (Danio rerio)

Pcmt [cytosol] (Drosophila melanogaster)

pcm-1 [cytosol] (Caenorhabditis elegans)

Homologues of PCMT1 [cytosol] (Sus scrofa)

pcm2 [cytosol] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001238978.1, NP_001347381.1, NP_001238982.1, NP_001347385.1, NP_005380.2

ENSEMBL

ENSP00000356354, ENST00000464889, ENSP00000420813, ENST00000367378, ENSG00000120265, ENSP00000356348, ENST00000367384

OpenTargets

ENSG00000120265

ZINC - Substances

PIMT_HUMAN

ZINC target

P22061

PRO

P22061

GlyGen

P22061

PDB

1KR5, 1I1N

IntEnz

2.1.1.77

GeneCards

PCMT1

HPA

ENSG00000120265-PCMT1

Pharos - Targets

P22061

HMDB Protein

HMDBP00412

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.706	19
UniProt:P49247 RPIA	2	RPIA [cytosol] (R-HSA-71304) RPIA A61V [cytosol] (R-HSA-5660009)	0.666	4
UniProt:P60520 GABARAPL2	3	GABARAPL2 [cytosol] (R-HSA-5671758) GABARAPL2(1-117) [cytosol] (R-HSA-5682641) GABARAPL2 [autophagosome membrane] (R-HSA-5683633)	0.564	2
UniProt:P0DTD1-PRO_0000449623 REP			0.564	2
UniProt:Q13155 AIMP2	1	AIMP2 [cytosol] (R-HSA-379576)	0.556	3

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