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CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
Stable Identifier
R-HSA-5676556
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
TNFR2 non-canonical NF-kB pathway (Homo sapiens)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Homo sapiens)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Homo sapiens)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Homo sapiens)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Homo sapiens)
Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Homo sapiens)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Homo sapiens)
Participants
components
CD40:CD40L trimer [plasma membrane]
(Homo sapiens)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol]
(Homo sapiens)
Participates
as an output of
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Homo sapiens)
as a member of
Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Homo sapiens)
Inferred To
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
(Bos taurus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
(Canis familiaris)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
(Danio rerio)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
(Gallus gallus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
(Mus musculus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
(Rattus norvegicus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
(Sus scrofa)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane]
(Xenopus tropicalis)
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