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PTPLA [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-5676076
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1, HACD1
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Fatty acyl-CoA biosynthesis (Homo sapiens)
Synthesis of very long-chain fatty acyl-CoAs (Homo sapiens)
PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Homo sapiens)
PTPLs [endoplasmic reticulum membrane] (Homo sapiens)
PTPLA [endoplasmic reticulum membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
18554506
Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases involved in very long-chain fatty acid synthesis
Ikeda, M
,
Kanao, Y
,
Yamanaka, M
,
Sakuraba, H
,
Igarashi, Y
,
Kihara, A
,
Mizutani, Y
FEBS Lett.
2008
External Reference Information
External Reference
UniProt:B0YJ81 HACD1
Gene Names
HACD1, PTPLA
Chain
chain:1-288
Reference Genes
BioGPS Gene:9200 HACD1
COSMIC (genes):HACD1 HACD1
CTD Gene:9200 HACD1
dbSNP Gene:9200 HACD1
ENSEMBL:ENSG00000165996 HACD1
ENSEMBL_homo_sapiens_GENE:ENSG00000165996.14 HACD1
HGNC:9639 HACD1
KEGG Gene (Homo sapiens):9200 HACD1
Monarch:9200 HACD1
NCBI Gene:9200 HACD1
OMIM:610467 HACD1
UCSC:B0YJ81 HACD1
Reference Transcript
RefSeq:NM_014241.3 HACD1
Other Identifiers
11729887_at
16712292
219654_PM_at
219654_at
3279986
3279987
3279988
3279989
3279992
3279996
3280001
3280005
3280009
3280010
57491_at
7932420
9200
A_23_P161352
GE58575
GO:0003824
GO:0005515
GO:0005783
GO:0005789
GO:0006629
GO:0006631
GO:0006633
GO:0006790
GO:0016020
GO:0016829
GO:0018812
GO:0019899
GO:0030148
GO:0030497
GO:0035338
GO:0042761
GO:0043226
GO:0055086
GO:0102158
GO:1901135
HMNXSV003013522
HMNXSV003056519
ILMN_1725791
PH_hs_0006264
TC10001075.hg
g7657481_3p_at
Participates
as a member of
PTPLs [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
PHS1 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
hpo-8 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
HACD1 [endoplasmic reticulum membrane]
(Bos taurus)
HACD1 [endoplasmic reticulum membrane]
(Canis familiaris)
HACD1 [endoplasmic reticulum membrane]
(Gallus gallus)
HACD1 [endoplasmic reticulum membrane]
(Sus scrofa)
hacd1 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Hacd1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Hacd1 [endoplasmic reticulum membrane]
(Mus musculus)
Hacd1 [endoplasmic reticulum membrane]
(Rattus norvegicus)
PTPLA [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
PTPLA [endoplasmic reticulum membrane]
(Plasmodium falciparum)
PTPLA [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_055056.3
OpenTargets
ENSG00000165996
GeneCards
B0YJ81
HPA
ENSG00000165996-HACD1
Ensembl
ENSG00000165996
,
ENST00000361271
,
ENSP00000355308
PRO
B0YJ81
Pharos - Targets
B0YJ81
Orphanet
22580
HMDB Protein
HMDBP11773
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13651 IL10RA
3
p-Y446-IL10RA [plasma membrane]
(R-HSA-6784810)
p-Y496-IL10RA [plasma membrane]
(R-HSA-6784793)
IL10RA [plasma membrane]
(R-HSA-449841)
0.556
3
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