p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol]

Stable Identifier
R-HSA-5675858
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Serine/threonine-protein kinase ULK1, ULK1_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9P2M4 TBC1D14
Expand all
External Reference Information
External Reference
UniProt:O75385 ULK1
Gene Names
ULK1, KIAA0722
Chain
chain:1-1050
Reference Genes
BioGPS Gene:8408 ULK1
COSMIC (genes):ULK1 ULK1
CTD Gene:8408 ULK1
dbSNP Gene:8408 ULK1
ENSEMBL:ENSG00000177169 ULK1
HGNC:12558 ULK1
KEGG Gene (Homo sapiens):8408 ULK1
Monarch:8408 ULK1
NCBI Gene:8408 ULK1
OMIM:603168 ULK1
UCSC:O75385 ULK1
Reference Transcript
Other Identifiers
0006200687
04150+2.7.11.1
04151+2.7.11.1
04714+2.7.11.1
04926+2.7.11.1
05163+2.7.11.1
05165+2.7.11.1
05170+2.7.11.1
11744271_a_at
16759350
209333_at
3438528
3438529
3438530
3438531
3438532
3438546
3438547
3438548
3438549
3438550
3438553
3438554
3438555
3438556
3438557
3438558
3438560
3438561
3438562
3438563
3438564
3438565
3438566
3438567
3438570
3438572
3438574
3438576
3438578
3438579
3438580
34827_at
4WNO
4WNP
5CI7
63990
6MNH
6QAS
7959957
8408
A_23_P72550
A_24_P73370
AAC32326
AB018265
AC131009
AF045458
BAA34442
CCDS9274
ENSG00000177169
ENSP00000324560
ENST00000321867
ENST00000321867.5
EntrezGene:8408
EntrezGene:ULK1
g3882164_3p_at
GE54394
GO:0000045
GO:0000166
GO:0000407
GO:0000902
GO:0003674
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005739
GO:0005741
GO:0005768
GO:0005773
GO:0005776
GO:0005783
GO:0005789
GO:0005829
GO:0006464
GO:0006468
GO:0006914
GO:0006950
GO:0007165
GO:0007409
GO:0008104
GO:0008150
GO:0009056
GO:0010506
GO:0010508
GO:0016020
GO:0016236
GO:0016241
GO:0016301
GO:0016310
GO:0016740
GO:0017137
GO:0018105
GO:0018107
GO:0019899
GO:0022607
GO:0030154
GO:0030424
GO:0031102
GO:0031175
GO:0031333
GO:0031410
GO:0031669
GO:0032045
GO:0032991
GO:0034045
GO:0040007
GO:0042594
GO:0042802
GO:0043167
GO:0043226
GO:0044403
GO:0044877
GO:0046777
GO:0048675
GO:0048856
GO:0051020
GO:0055037
GO:0065003
GO:0075044
GO:0097629
GO:0097632
GO:0097635
GO:1990316
GO:2000786
HGNC:12558
HPA063990
ILMN_1705144
ILMN_1735052
ILMN_1744560
ILMN_1761288
IPR000719
IPR008271
IPR011009
IPR016237
IPR017441
IPR022708
MIM:603168
NM_003565
NP_003556
PF00069
PF12063
PH_hs_0003343
SM00220
TC12001049.hg
ULK1
ULK1-201
UPI00001FB0D9
XM_011538798
XM_011538799
XP_011537100
XP_011537101
XR_001748883
Participant Of
hasComponent
Other forms of this molecule
ULK1 [cytosol]
ULK1 [mitochondrial outer membrane]
p-T180,S317,S467,S556,S638,T575-ULK1 [endoplasmic reticulum membrane]
p-S758-ULK1 [cytosol]
p-S317,467,556,638,T575-ULK1 [cytosol]
ULK1 [recycling endosome]
Inferred To
Ghost homologue of p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Schizosaccharomyces pombe)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Bos taurus)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Caenorhabditis elegans)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Canis familiaris)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Danio rerio)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Dictyostelium discoideum)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Drosophila melanogaster)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Gallus gallus)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Mus musculus)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Rattus norvegicus)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Sus scrofa)
phospho-p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-threonine at 180
Coordinate
180
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 317
Coordinate
317
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 467
Coordinate
467
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 556
Coordinate
556
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 575
Coordinate
575
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 638
Coordinate
638
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Investigational
GeneCards
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (24)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:O75143 ATG13  3 0.847 10
 UniProt:Q8TDY2 RB1CC1  3 0.773 9
 UniProt:P42345 MTOR  2 0.702 7
 IntAct:EBI-4399559 UBIQ      0.697 5
 UniProt:Q96LT7-1 C9ORF72      0.688 5
 UniProt:Q13131 PRKAA1  3 0.688 3
 UniProt:P54619 PRKAG1  2 0.688 3
 UniProt:Q9BXW4 MAP1LC3C  3 0.656 3
 UniProt:Q9GZQ8 MAP1LC3B  3 0.656 3
 UniProt:Q9BSB4 ATG101  2 0.643 4
 UniProt:Q9Y478 PRKAB1  2 0.641 3
 UniProt:Q9C0C7 AMBRA1  2 0.641 3
 UniProt:P42858 HTT  1 0.612 8
 UniProt:O95166 GABARAP  3 0.609 2
 UniProt:P60520 GABARAPL2  3 0.602 3
 UniProt:Q96LT7-2 C9ORF72      0.591 4
 UniProt:O75385 ULK1  7 0.589 3
 UniProt:P54646 PRKAA2  4 0.589 2
 UniProt:Q9H0R8 GABARAPL1  3 0.544 2
 UniProt:Q9P2M4 TBC1D14  1 0.543 4
 UniProt:Q9C0C7-3 AMBRA1      0.524 4
 UniProt:Q8N122 RPTOR  3 0.499 3
 UniProt:Q9Y4K3 TRAF6  8 0.499 2
 UniProt:P04629 NTRK1  4 0.499 2