LAMTOR3 (also known as MEK partner 1, MP1) exists in an obligatory complex with LAMTOR2 (p14) at the endosomal membrane where they act as a scaffold and promote MAPK activation (Schaeffer et al, 1998; Teis et al, 2002; Teis et al, 2006; Sharma et al, 2005). The LAMTOR2/LAMTOR3 complex may also be part of a larger molecular weight complex at the endosome that includes the MAPK organizer protein MORG1 (Vomastek et al, 2004; Sharma et al, 2005; reviewed in Matallanas et al, 2011).
Teis, D, Huber, LA, Wunderlich, W
Sharma, C, Eblen, ST, Weber, MJ, Catling, AD, Tarcsafalvi, A, Vomastek, T, Schaeffer, HJ
Teis, D, Kurzbauer, R, Villunger, A, de Araujo, ME, Geley, S, Erlacher, M, Offterdinger, M, Huber, LA, Taub, N, Hess, MW, Klein, C, Hilber, D, Bohn, G
Eblen, ST, Weber, MJ, Collier, LS, Catling, AD, Schaeffer, HJ, Krauss, A
Weber, MJ, Tarcsafalvi, A, Vomastek, T, Schaeffer, HJ, Bissonette, EA, Smolkin, ME
Romano, D, Matallanas, D, Rauch, J, Zebisch, A, Birtwistle, M, Kolch, W, von Kriegsheim, A
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