LAMTOR3 (also known as MEK partner 1, MP1) exists in an obligatory complex with LAMTOR2 (p14) at the endosomal membrane where they act as a scaffold and promote MAPK activation (Schaeffer et al, 1998; Teis et al, 2002; Teis et al, 2006; Sharma et al, 2005). The LAMTOR2/LAMTOR3 complex may also be part of a larger molecular weight complex at the endosome that includes the MAPK organizer protein MORG1 (Vomastek et al, 2004; Sharma et al, 2005; reviewed in Matallanas et al, 2011).
Sharma, C, Vomastek, T, Tarcsafalvi, A, Catling, AD, Schaeffer, HJ, Eblen, ST, Weber, MJ
Teis, D, Wunderlich, W, Huber, LA
Teis, D, Taub, N, Kurzbauer, R, Hilber, D, de Araujo, ME, Erlacher, M, Offterdinger, M, Villunger, A, Geley, S, Bohn, G, Klein, C, Hess, MW, Huber, LA
Schaeffer, HJ, Catling, AD, Eblen, ST, Collier, LS, Krauss, A, Weber, MJ
Vomastek, T, Schaeffer, HJ, Tarcsafalvi, A, Smolkin, ME, Bissonette, EA, Weber, MJ
Matallanas, D, Birtwistle, M, Romano, D, Zebisch, A, Rauch, J, von Kriegsheim, A, Kolch, W
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