Interaction of MAPK pathway components with LAMTOR2, 3 and MORG1 facilitates pathway activation in response to varied stimuli, resulting in the phosphorylation of MAP2K and MAPK proteins at conserved sites in their activation loops (Schaeffer et al, 1998; Teis et al, 2002; Teis et al, 2006; Vomastek et al, 2004; Sharma et al, 2005; reviewed in Matallanas et al, 2011).
Sharma, C, Vomastek, T, Tarcsafalvi, A, Catling, AD, Schaeffer, HJ, Eblen, ST, Weber, MJ
Teis, D, Wunderlich, W, Huber, LA
Teis, D, Taub, N, Kurzbauer, R, Hilber, D, de Araujo, ME, Erlacher, M, Offterdinger, M, Villunger, A, Geley, S, Bohn, G, Klein, C, Hess, MW, Huber, LA
Schaeffer, HJ, Catling, AD, Eblen, ST, Collier, LS, Krauss, A, Weber, MJ
Vomastek, T, Schaeffer, HJ, Tarcsafalvi, A, Smolkin, ME, Bissonette, EA, Weber, MJ
Matallanas, D, Birtwistle, M, Romano, D, Zebisch, A, Rauch, J, von Kriegsheim, A, Kolch, W
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