Binding to activated RAS stimulates the ubiquitinase activity of BRAP, promoting autoubiquitination and relieving the inhibition of KSR1 (Methany et al, 2004; Chen et al, 2008; Methany et al, 2009).
White, MA, Kortum, RL, Lewis, RE, Razidlo, GL, Matheny, SA, Chen, C
White, MA, Lewis, RE, Chen, C
White, MA, Matheny, SA
ubiquitin protein ligase activity of p21 RAS:GTP:BRAP [plasma membrane]
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