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TNFRSF11B [plasma membrane]
Stable Identifier
R-HSA-5672848
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Tumor necrosis factor receptor superfamily member 11B, TR11B_HUMAN, OPG (osteoprotegerin)
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
TNFR2 non-canonical NF-kB pathway (Homo sapiens)
TNFs bind their physiological receptors (Homo sapiens)
TNFSF11 binds TNFRSF11A, B (Homo sapiens)
TNFRSF11B [plasma membrane] (Homo sapiens)
TNFSF11,sTNFSF11 trimer:3xTNFRSF11B [plasma membrane] (Homo sapiens)
TNFRSF11B [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00300 TNFRSF11B
Gene Names
TNFRSF11B, OCIF, OPG
Chain
signal peptide:1-21, chain:22-401
Reference Genes
BioGPS Gene:4982 TNFRSF11B
COSMIC (genes):TNFRSF11B TNFRSF11B
CTD Gene:4982 TNFRSF11B
dbSNP Gene:4982 TNFRSF11B
ENSEMBL:ENSG00000164761 TNFRSF11B
HGNC:11909 TNFRSF11B
Monarch:4982 TNFRSF11B
NCBI Gene:4982 TNFRSF11B
OMIM:602643 TNFRSF11B
UCSC:O00300 TNFRSF11B
Reference Transcript
RefSeq:NM_002546.3 TNFRSF11B
Other Identifiers
11730319_at
17080486
204932_PM_at
204932_at
204933_PM_s_at
204933_s_at
3150466
3150467
3150468
3150469
3150470
3150471
3150472
3150473
3150476
3150477
37611_at
4982
8152512
A_23_P71530
A_24_P192485
GE60460
GO:0001501
GO:0005125
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0006915
GO:0007165
GO:0007584
GO:0009410
GO:0010804
GO:0012501
GO:0030198
GO:0030312
GO:0031012
GO:0032026
GO:0038023
GO:0042489
GO:0043235
GO:0043627
GO:0045671
GO:0045779
GO:0046685
GO:0048018
GO:0048856
GO:0060089
GO:0098772
GO:1904399
HMNXSV003003662
Hs.81791.0.S2_3p_at
ILMN_1676663
PH_hs_0004673
TC08001552.hg
U94332_at
g4507566_3p_a_at
Participates
as a component of
TNFSF11,sTNFSF11 trimer:3xTNFRSF11B [plasma membrane] (Homo sapiens)
as an input of
TNFSF11 binds TNFRSF11A, B (Homo sapiens)
Inferred To
Tnfrsf11b [plasma membrane]
(Mus musculus)
Tnfrsf11b [plasma membrane]
(Rattus norvegicus)
tnfrsf11b [plasma membrane]
(Xenopus tropicalis)
TNFRSF11B [plasma membrane]
(Bos taurus)
TNFRSF11B [plasma membrane]
(Canis familiaris)
TNFRSF11B [plasma membrane]
(Gallus gallus)
TNFRSF11B [plasma membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
1882
ENSEMBL
ENSP00000297350
,
ENST00000297350
OpenTargets
ENSG00000164761
HPA
ENSG00000164761-TNFRSF11B
PRO
O00300
Pharos - Targets
O00300
Orphanet
TNFRSF11B
HMDB Protein
HMDBP02763
PDB
3URF
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14788 TNFSF11
2
TNFSF11 [plasma membrane]
(R-HSA-5667141)
sTNFSF11 [extracellular region]
(R-HSA-5676547)
0.618
3
UniProt:P49768-2 PSEN1
0.556
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:Q9Y6Q6 TNFRSF11A
1
TNFRSF11A [plasma membrane]
(R-HSA-5668756)
0.544
7
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