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p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
Stable Identifier
R-HSA-5672729
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Oncogenic MAPK signaling (Homo sapiens)
Signaling by RAF1 mutants (Homo sapiens)
Phosphorylation of RAF1 mutants (Homo sapiens)
p21 RAS:GTP:RAF1 mutant heterodimers [plasma membrane] (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
RAF1 mutants show enhanced heterodimerization with BRAF (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
p21 RAS:GTP:RAF1 mutant heterodimers [plasma membrane] (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
MAP2K and MAPK activation (Homo sapiens)
RAF phosphorylates MAP2K dimer (Homo sapiens)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Homo sapiens)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
RAF activation (Homo sapiens)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
Phosphorylation of RAF (Homo sapiens)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
Raf dimer inhibitors bind RAF heterodimers (Homo sapiens)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Homo sapiens)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Homo sapiens)
Participants
components
'activator' RAF:YWHAB dimer [cytosol]
(Homo sapiens)
p21 RAS:GTP [plasma membrane]
(Homo sapiens)
Participates
as an input of
RAF1 mutants show enhanced heterodimerization with BRAF (Homo sapiens)
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Homo sapiens)
as a component of
p21 RAS:GTP:RAF1 mutant heterodimers [plasma membrane] (Homo sapiens)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
as an output of
"Activator" RAF:YWHAB dimer binds RAS:GTP (Homo sapiens)
Inferred To
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Caenorhabditis elegans)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Canis familiaris)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Drosophila melanogaster)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Gallus gallus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Mus musculus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Plasmodium falciparum)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Rattus norvegicus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane]
(Sus scrofa)
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