Reactome | p-S311,T602 KSR1:MARK3 [plasma membrane]

p-S311,T602 KSR1:MARK3 [plasma membrane]

Stable Identifier

R-HSA-5672699

Type

Complex

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- MAPK family signaling cascades (Homo sapiens)
  - MAPK1/MAPK3 signaling (Homo sapiens)
    - RAF/MAP kinase cascade (Homo sapiens)
      - MAP2K and MAPK activation (Homo sapiens)
        
        Dissociation of RAS:RAF complex (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        Dual mechanism MAP2K inhibitors bind MAP2Ks (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        Dual mechanism MAPK inhibitors bind MAPKs (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MAP2Ks and MAPKs bind to the activated RAF complex (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MAP2Ks phosphorylate MAPKs (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        RAF phosphorylates MAP2K dimer (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        Single mechanism MAPK inhibitors bind phosphorylated MAPK (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
      - RAF activation (Homo sapiens)
        
        Phosphorylation of RAF (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)

Participants

components

Participates

as a candidate of

activated RAF/KSR1 [plasma membrane] (Homo sapiens)

Inferred To

p-S311,T602 KSR1:MARK3 [plasma membrane] (Bos taurus)

p-S311,T602 KSR1:MARK3 [plasma membrane] (Caenorhabditis elegans)

p-S311,T602 KSR1:MARK3 [plasma membrane] (Canis familiaris)

p-S311,T602 KSR1:MARK3 [plasma membrane] (Drosophila melanogaster)

p-S311,T602 KSR1:MARK3 [plasma membrane] (Mus musculus)

p-S311,T602 KSR1:MARK3 [plasma membrane] (Plasmodium falciparum)

p-S311,T602 KSR1:MARK3 [plasma membrane] (Rattus norvegicus)

p-S311,T602 KSR1:MARK3 [plasma membrane] (Sus scrofa)

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