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RAPGEF2 [cytosol]
Stable Identifier
R-HSA-5672599
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
RAPGEF2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y4G8 RAPGEF2
Gene Names
RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Chain
chain:1-1499
Reference Genes
BioGPS Gene:9693 RAPGEF2
COSMIC (genes):RAPGEF2 RAPGEF2
CTD Gene:9693 RAPGEF2
dbSNP Gene:9693 RAPGEF2
ENSEMBL:ENSG00000109756 RAPGEF2
ENSEMBL:ENSG00000109756.10 RAPGEF2
HGNC:16854 RAPGEF2
KEGG Gene (Homo sapiens):9693 RAPGEF2
Monarch:9693 RAPGEF2
NCBI Gene:9693 RAPGEF2
OMIM:609530 RAPGEF2
UCSC:Q9Y4G8 RAPGEF2
Reference Transcript
RefSeq:NM_014247.2 RAPGEF2
Other Identifiers
11721607_at
11721608_s_at
16971995
203096_PM_s_at
203096_s_at
203097_PM_s_at
203097_s_at
215992_PM_s_at
215992_s_at
2749751
2749752
2749772
2749773
2749775
2749779
2749780
2749782
2749785
2749786
2749788
2749789
2749790
2749791
2749797
2749798
2749800
2749801
2749802
2749803
2749805
2749806
2749810
2749811
2749812
2749814
2749815
2749816
2749817
2749819
2749820
2749821
2749822
32026_s_at
34745_at
8098121
9693
A_14_P102174
A_14_P123999
A_14_P125552
A_23_P133095
A_33_P3334743
GE53049
GO:0000165
GO:0001568
GO:0001764
GO:0005085
GO:0005096
GO:0005509
GO:0005515
GO:0005737
GO:0005768
GO:0005770
GO:0005829
GO:0005886
GO:0005911
GO:0005923
GO:0006508
GO:0007165
GO:0007186
GO:0007218
GO:0007264
GO:0007265
GO:0007399
GO:0008285
GO:0008289
GO:0010976
GO:0012501
GO:0016020
GO:0016324
GO:0019933
GO:0019992
GO:0021591
GO:0021884
GO:0023052
GO:0030033
GO:0030139
GO:0030154
GO:0030165
GO:0030552
GO:0031175
GO:0031410
GO:0031547
GO:0031697
GO:0032092
GO:0032486
GO:0032991
GO:0034330
GO:0035556
GO:0036211
GO:0038180
GO:0043005
GO:0043025
GO:0043226
GO:0043547
GO:0043950
GO:0045202
GO:0045860
GO:0048022
GO:0048167
GO:0048471
GO:0048856
GO:0048870
GO:0050699
GO:0050774
GO:0061028
GO:0070161
GO:0070300
GO:0070374
GO:0071320
GO:0071321
GO:0071880
GO:0072659
GO:0090557
GO:0098772
GO:1901888
GO:1990090
GO:2000481
GO:2000670
GO:2001214
GO:2001224
HMNXSV003013760
Hs.154545.0.S1_3p_a_at
Hs.154545.2.S1_3p_a_at
PH_hs_0018074
g7657260_3p_a_at
Participates
as a member of
RAS GEFs [plasma membrane] (Homo sapiens)
Inferred To
Homologues of RAPGEF2 [cytosol]
(Danio rerio)
Homologues of RAPGEF2 [cytosol]
(Dictyostelium discoideum)
gefD [cytosol]
(Dictyostelium discoideum)
RAPGEF2 [cytosol]
(Bos taurus)
RAPGEF2 [cytosol]
(Caenorhabditis elegans)
RAPGEF2 [cytosol]
(Canis familiaris)
RAPGEF2 [cytosol]
(Danio rerio)
RAPGEF2 [cytosol]
(Mus musculus)
RAPGEF2 [cytosol]
(Rattus norvegicus)
gefM [cytosol]
(Dictyostelium discoideum)
gefC [cytosol]
(Dictyostelium discoideum)
PDZ-GEF [cytosol]
(Drosophila melanogaster)
gefN [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_055062.1
OpenTargets
ENSG00000109756
GeneCards
Q9Y4G8
HPA
ENSG00000109756-RAPGEF2
Ensembl
ENSP00000264431
,
ENST00000264431
,
ENSG00000109756
PRO
Q9Y4G8
Pharos - Targets
Q9Y4G8
Orphanet
29073
HMDB Protein
HMDBP01123
PDB
6QDT
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P46937 YAP1
7
p-Y407-YAP1 [nucleoplasm]
(R-HSA-8956661)
p-Y-YAP1 [cytosol]
(R-HSA-8937843)
p-Y-YAP1 [nucleoplasm]
(R-HSA-8937857)
p-S127-YAP1 [cytosol]
(R-HSA-2028553)
p-5S-YAP1 [cytosol]
(R-HSA-2028554)
YAP1 [cytosol]
(R-HSA-1253345)
YAP1 [nucleoplasm]
(R-HSA-1253322)
0.527
2
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