Reactome | FLNA binds PAK1

FLNA binds PAK1

Stable Identifier

R-HSA-5669240

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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The CRIB domain of PAK1 binds to the C-terminal part (repeat 23) of filamin A (FLNA). The interaction is enhanced upon PAK1 activation (Vadlamudi et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
12198493	Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1 Stossel, TP, Li, F, Kumar, R, Vadlamudi, RK, Nguyen, D, Ohta, Y, Adam, L	Nat. Cell Biol.	2002