FLNA binds PAK1

Stable Identifier
R-HSA-5669240
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
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FLNA binds PAK1
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The CRIB domain of PAK1 binds to the C-terminal part (repeat 23) of filamin A (FLNA). The interaction is enhanced upon PAK1 activation (Vadlamudi et al. 2002).

Literature References
PubMed ID Title Journal Year
12198493 Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1

Vadlamudi, RK, Li, F, Adam, L, Nguyen, D, Ohta, Y, Stossel, TP, Kumar, R

Nat. Cell Biol. 2002
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Orthologous Events
FLNA binds PAK1 (Bos taurus)
FLNA binds PAK1 (Canis familiaris)
FLNA binds PAK1 (Danio rerio)
FLNA binds PAK1 (Mus musculus)
FLNA binds PAK1 (Rattus norvegicus)
FLNA binds PAK1 (Sus scrofa)
FLNA binds PAK1 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2015-02-02)
Rivero Crespo, F  (2014-12-26)
Created
Orlic-Milacic, M  (2015-01-31)