MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex

Stable Identifier
R-HSA-5668978
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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MYLK (MLCK) is a Ca2+/calmodulin-dependent myosin light chain kinase that phosphorylates myosin regulatory light chains (MRLC) MYL9 and MYL12B at threonine T19 and serine S20 (also labeled in literature as T18 and S19) (Ikebe and Hartshorne 1985, Ikebe et al. 1986).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
myosin light chain kinase activity of MYLK:Ca2+:CALM1 [cytosol]
Physical Entity
Activity
This event is regulated
Inferred From
Authored
Created