RORA, EP300, PPARGC1A bind NR1D1 gene

Stable Identifier
R-HSA-5663273
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RORA, EP300, PPARGC1A bind NR1D1 gene
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As inferred from mouse, RORA binds RRE DNA elements and recruits the coactivators PGC-1alpha (PPARGC1A) and p300 (EP300, a histone acetylase). RORA binds the NR1D1 (REV-ERBA) promoter and activates transcription.
Literature References
PubMed ID Title Journal Year
12377782 Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha

Fontaine, C, Monte, D, Fruchart, J, Raspè, E, Mautino, G, Fruchart, JC, Duez, H, Barbier, O, Staels, B, Duval, C

J Biol Chem 2002
Participants
Input
Output
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as an event of
Inferred From
Rora, Ep300, Ppargc1a bind Nr1d1 gene (Mus musculus)
Authored
May, B  (2015-01-16)
Reviewed
Delaunay, F  (2012-01-28)
Created
May, B  (2015-01-17)
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