p-BMAL1:p-CLOCK,NPAS2 binds BHLHE40 gene

Stable Identifier
R-HSA-5663170
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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BMAL1:CLOCK (ARNTL:CLOCK) heterodimers bind E-boxes in the promoter of the DEC1 (BHLHE40, BHLHB2) gene and activate transcription of DEC1.

Literature References
PubMed ID Title Journal Year
14672706 A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation

Kawamoto, T, Noshiro, M, Sato, F, Maemura, K, Takeda, N, Nagai, R, Iwata, T, Fujimoto, K, Furukawa, M, Miyazaki, K, Honma, S, Honma, K, Kato, Y

Biochem Biophys Res Commun 2004
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