Reactome | SLCO1B3 I562* [plasma membrane]

SLCO1B3 I562* [plasma membrane]

Stable Identifier

R-HSA-5661201

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

OATP-8, Solute carrier organic anion transporter family member 1B3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NPD5 SLCO1B3

Gene Names

SLCO1B3, LST2, OATP1B3, OATP8, SLC21A8

Chain

chain:1-702

Reference Genes

BioGPS Gene:28234 SLCO1B3

COSMIC (genes):SLCO1B3 SLCO1B3

CTD Gene:28234 SLCO1B3

dbSNP Gene:28234 SLCO1B3

ENSEMBL:ENSG00000111700 SLCO1B3

HGNC:10961 SLCO1B3

KEGG Gene (Homo sapiens):28234 SLCO1B3

Monarch:28234 SLCO1B3

NCBI Gene:28234 SLCO1B3

OMIM:605495 SLCO1B3

UCSC:Q9NPD5 SLCO1B3

Reference Transcript

RefSeq:NM_019844.3 SLCO1B3

Other Identifiers

0005130193

11732569_at

16749036

206354_at

28234

3407630

3407631

3407632

3407633

3407639

3407640

3407643

3407644

3407645

3407646

3407649

3407650

3407652

3407653

3407655

3407656

3407657

3407660

3407663

3407666

3407667

3407668

3407686

3407689

3407690

3407693

7954330

A_14_P102835

A_14_P108697

A_14_P133603

A_23_P105475

A_33_P3364089

GE82482

GO:0003674

GO:0005515

GO:0005575

GO:0005886

GO:0005887

GO:0006810

GO:0006811

GO:0008150

GO:0008514

GO:0009056

GO:0015125

GO:0015347

GO:0015711

GO:0015721

GO:0016020

GO:0016021

GO:0016323

GO:0022857

GO:0034641

GO:0042167

GO:0043252

GO:0055085

HMNXSV003006405

ILMN_1687319

PH_hs_0030139

TC12002282.hg

g9790232_3p_at

Other forms of this molecule

SLCO1B3 [plasma membrane]

Modified Residues

Name

Nonsense mutation at L-isoleucine 562

Coordinate

562

PsiMod

L-isoleucine removal [MOD:01640]

A protein modification that effectively removes or replaces an L-isoleucine.

Disease

Name	Identifier	Synonyms
bilirubin metabolic disorder	DOID:2741	hyperbilirubinemia, hereditary hyperbilirubinemia

Cross References

RefSeq

NP_062818.1

ZINC - World Drugs

SO1B3_HUMAN

Guide to Pharmacology - Targets

1221

OpenTargets

ENSG00000111700

ZINC - FDA approved

SO1B3_HUMAN

ZINC - Substances

SO1B3_HUMAN

ZINC target

Q9NPD5

ZINC - Biogenic

SO1B3_HUMAN

PRO

Q9NPD5

GlyGen

Q9NPD5

ZINC - Investigational

SO1B3_HUMAN

ZINC - Metabolites

SO1B3_HUMAN

GeneCards

Q9NPD5

HPA

ENSG00000111700-SLCO1B3

Ensembl

ENSG00000111700, ENST00000261196, ENST00000381545, ENSP00000261196, ENSP00000370956

Pharos - Targets

Q9NPD5

ZINC - Predictions - Purchasable

SO1B3_HUMAN

Orphanet

20820

HMDB Protein

HMDBP00446