CCL17 and CCL22 genes are transcribed

Stable Identifier
R-HSA-5660965
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
CCL17 and CCL22 genes are transcribed
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

RELB-p52 NF-kB complex binds to DNA and mediate the expression of chemokines (CCL17) and CCL22 after CLEC7A (dectin-1) triggering.

Literature References
PubMed ID Title Journal Year
19122653 Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk

Wevers, B, Litjens, M, Geijtenbeek, TB, Bruijns, SC, Gringhuis, SI, den Dunnen, J, van der Vlist, M

Nat. Immunol. 2009
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
p-S276-RELA:RELB [nucleoplasm] (Homo sapiens)
Positively by
Regulator
p52:RELB [nucleoplasm] (Homo sapiens)
Authored
Garapati, P V  (2015-01-05)
Reviewed
Geijtenbeek, TB  (2014-09-02)
Created
Garapati, P V  (2015-01-07)
Cite Us!