Expression of SNCB

Stable Identifier
R-HSA-5660530
Type
Reaction [omitted]
Species
Homo sapiens
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The SNCB (beta-synuclein) gene is transcribed to yield mRNA which is translated to yield protein (Lavedan et al. 1998). Transcription of SNCB is up-regulated by copper via a metal response binding element in the 5' promoter that binds MTF1 (McHugh et al. 2011).

Literature References
PubMed ID Title Journal Year
9806846 Genomic organization and expression of the human beta-synuclein gene (SNCB)

Lavedan, C, Leroy, E, Torres, R, Dehejia, A, Dutra, A, Buchholtz, S, Nussbaum, RL, Polymeropoulos, MH

Genomics 1998
21386983 Transcriptional regulation of the beta-synuclein 5'-promoter metal response element by metal transcription factor-1

McHugh, PC, Wright, JA, Brown, DR

PLoS ONE 2011
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