Expression of CSRP1

Stable Identifier
R-HSA-5660503
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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The CSRP1 gene is transcribed to yield mRNA which is translated to yield protein. Expression of CSRP1 is activated by zinc via MTF1 (Hardyman et al. 2016). As inferred from the mouse homolog, expression of CSRP1 is activated by cadmium via MTF1.

Literature References
PubMed ID Title Journal Year
26824222 Zinc sensing by metal-responsive transcription factor 1 (MTF1) controls metallothionein and ZnT1 expression to buffer the sensitivity of the transcriptome response to zinc

Hardyman, JE, Tyson, J, Jackson, KA, Aldridge, C, Cockell, SJ, Wakeling, LA, Valentine, RA, Ford, D

Metallomics 2016
1374386 Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc

Wang, X, Lee, G, Liebhaber, SA, Cooke, NE

J. Biol. Chem. 1992
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Summation

As inferred from mouse homologs, MTF1 binds and activates the CSRP1 promoter (Wimmer et al. 2005).

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