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MTF1 [nucleoplasm]
Stable Identifier
R-HSA-5660367
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Metal regulatory transcription factor 1, MTF1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Response to metal ions (Homo sapiens)
MTF1 activates gene expression (Homo sapiens)
Expression of CSRP1 (Homo sapiens)
MTF1 dimer:12Zn2+:CSRP1 gene [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+ [nucleoplasm] (Homo sapiens)
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
MTF1 [nucleoplasm] (Homo sapiens)
Expression of SNCB (Homo sapiens)
MTF1 dimer:12Zn2+:SNCB gene [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+ [nucleoplasm] (Homo sapiens)
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
MTF1 [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+ binds CSRP1 gene (Homo sapiens)
MTF1 dimer:12Zn2+ [nucleoplasm] (Homo sapiens)
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
MTF1 [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+:CSRP1 gene [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+ [nucleoplasm] (Homo sapiens)
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
MTF1 [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein) (Homo sapiens)
MTF1 dimer:12Zn2+ [nucleoplasm] (Homo sapiens)
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
MTF1 [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+:SNCB gene [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+ [nucleoplasm] (Homo sapiens)
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
MTF1 [nucleoplasm] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
Activation of gene expression by SREBF (SREBP) (Homo sapiens)
Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) (Homo sapiens)
MTF1 dimer:12Zn2+:HMGCR gene [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+ [nucleoplasm] (Homo sapiens)
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
MTF1 [nucleoplasm] (Homo sapiens)
Regulation of lipid metabolism by PPARalpha (Homo sapiens)
PPARA activates gene expression (Homo sapiens)
Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) (Homo sapiens)
MTF1 dimer:12Zn2+:HMGCR gene [nucleoplasm] (Homo sapiens)
MTF1 dimer:12Zn2+ [nucleoplasm] (Homo sapiens)
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
MTF1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14872 MTF1
Gene Names
MTF1
Chain
initiator methionine:, chain:2-753
Reference Genes
BioGPS Gene:4520 MTF1
COSMIC (genes):MTF1 MTF1
CTD Gene:4520 MTF1
dbSNP Gene:4520 MTF1
ENSEMBL:ENSG00000188786 MTF1
ENSEMBL_homo_sapiens_GENE:ENSG00000188786.10 MTF1
HGNC:7428 MTF1
KEGG Gene (Homo sapiens):4520 MTF1
Monarch:4520 MTF1
NCBI Gene:4520 MTF1
OMIM:600172 MTF1
UCSC:Q14872 MTF1
Reference Transcript
RefSeq:NM_005955.2 MTF1
RefSeq:XM_011541491.2 MTF1
Other Identifiers
11722388_at
11722389_at
11722390_a_at
11722391_at
11751285_a_at
16685482
16685489
205322_PM_s_at
205322_s_at
205323_PM_s_at
205323_s_at
227150_PM_at
227150_at
2407396
2407397
2407398
2407399
2407400
2407401
2407402
2407403
2407404
2407406
2407407
2407408
2407409
2407410
2407411
2407412
38945_at
4041689
4041691
4041693
4041695
4041696
4041697
4041699
4041700
4041701
4041702
4041704
4041705
4041706
4041707
4041708
4041709
4041710
4041711
4041712
4041713
4041714
4043924
4043925
4043927
4043928
4043929
4043930
4043932
4043933
4043934
4043940
4043941
4043942
4520
51208_at
65662_at
7915084
7915091
A_23_P74241
A_33_P3294237
GE79676
GE876581
GO:0000978
GO:0000987
GO:0001228
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006351
GO:0006355
GO:0006357
GO:0006979
GO:0007417
GO:0010038
GO:0035035
GO:0043226
GO:0045893
GO:0045944
GO:0046686
GO:0046872
GO:0048856
GO:0071294
GO:0140110
GO:1990079
GO:1990837
HMNXSV003004496
Hs.211581.0.A1_3p_a_at
Hs.323867.0.A1_3p_at
ILMN_1763828
PH_hs_0026548
PH_hs_0039020
TC01002525.hg
TC01002526.hg
TC01005410.hg
X78710_at
g5174588_3p_a_at
Participates
as a component of
MTF1:6Zn2+ [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_005946.2
,
XP_011539793.1
OpenTargets
ENSG00000188786
HPA
ENSG00000188786-MTF1
GeneCards
Q14872
Ensembl
ENSP00000362127
,
ENSG00000188786
,
ENST00000373036
PRO
Q14872
Pharos - Targets
Q14872
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