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DAB2IP [cytosol]
Stable Identifier
R-HSA-5658238
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
Regulation of RAS by GAPs (Homo sapiens)
RAS GAPs bind RAS:GTP (Homo sapiens)
RAS GAPs [cytosol] (Homo sapiens)
DAB2IP [cytosol] (Homo sapiens)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Homo sapiens)
RAS GAPs [cytosol] (Homo sapiens)
DAB2IP [cytosol] (Homo sapiens)
RAS GAPs stimulate RAS GTPase activity (Homo sapiens)
RAS GAPs [cytosol] (Homo sapiens)
DAB2IP [cytosol] (Homo sapiens)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Homo sapiens)
RAS GAPs [cytosol] (Homo sapiens)
DAB2IP [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5VWQ8 DAB2IP
Gene Names
DAB2IP, AF9Q34, AIP1, KIAA1743
Chain
chain:1-1189
Reference Genes
BioGPS Gene:153090 DAB2IP
COSMIC (genes):DAB2IP DAB2IP
CTD Gene:153090 DAB2IP
dbSNP Gene:153090 DAB2IP
ENSEMBL:ENSG00000136848 DAB2IP
ENSEMBL_homo_sapiens_GENE:ENSG00000136848.19 DAB2IP
HGNC:17294 DAB2IP
KEGG Gene (Homo sapiens):153090 DAB2IP
Monarch:153090 DAB2IP
NCBI Gene:153090 DAB2IP
OMIM:609205 DAB2IP
UCSC:Q5VWQ8 DAB2IP
Reference Transcript
RefSeq:NM_138709.2 DAB2IP
RefSeq:XM_011518271.2 DAB2IP
RefSeq:XM_011518270.2 DAB2IP
RefSeq:XM_017014300.1 DAB2IP
RefSeq:NM_032552.3 DAB2IP
RefSeq:XM_005251719.4 DAB2IP
Other Identifiers
11719165_s_at
11719166_x_at
11732484_a_at
153090
17088701
225020_PM_at
225020_at
228942_PM_s_at
228942_s_at
3187835
3187836
3187855
3187856
3187857
3187863
3187872
3187873
3187880
3187889
3187891
3187892
3187893
3187894
3187896
3187898
3187903
3187904
3187906
3187908
3187909
3187910
3187911
3187912
3187913
3187914
3187915
3187916
3187918
3187919
3187922
3187925
3187927
3187928
3187929
3187930
3187931
3187932
3187933
45741_at
45742_g_at
51735_s_at
72473_at
8157610
91760_at
A_23_P123848
A_24_P149704
GE79900
GO:0000122
GO:0001525
GO:0002376
GO:0005096
GO:0005123
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006915
GO:0006954
GO:0006986
GO:0007049
GO:0008285
GO:0008289
GO:0008625
GO:0010596
GO:0010633
GO:0010719
GO:0010976
GO:0012501
GO:0016020
GO:0016525
GO:0017124
GO:0019900
GO:0019901
GO:0021814
GO:0021819
GO:0023052
GO:0030139
GO:0030154
GO:0030163
GO:0030424
GO:0030425
GO:0030948
GO:0031334
GO:0031410
GO:0031434
GO:0031435
GO:0032088
GO:0032266
GO:0032809
GO:0034144
GO:0034260
GO:0034330
GO:0034620
GO:0035148
GO:0035556
GO:0035591
GO:0035924
GO:0036211
GO:0036312
GO:0036324
GO:0042059
GO:0042177
GO:0042802
GO:0042803
GO:0042995
GO:0043025
GO:0043065
GO:0043087
GO:0043122
GO:0043123
GO:0043124
GO:0043184
GO:0043226
GO:0043254
GO:0043407
GO:0043410
GO:0043507
GO:0043539
GO:0043548
GO:0044300
GO:0044301
GO:0044877
GO:0045087
GO:0045296
GO:0045732
GO:0045892
GO:0045944
GO:0046330
GO:0046580
GO:0048147
GO:0048812
GO:0048856
GO:0048870
GO:0050680
GO:0051721
GO:0051726
GO:0051898
GO:0060090
GO:0065003
GO:0070059
GO:0070273
GO:0070317
GO:0070373
GO:0071222
GO:0071347
GO:0071356
GO:0071364
GO:0071889
GO:0071901
GO:0071902
GO:0072577
GO:0090090
GO:0090129
GO:0098542
GO:0098772
GO:1900006
GO:1900744
GO:1900747
GO:1901800
GO:1903896
GO:1990032
GO:1990597
GO:2001224
GO:2001235
HMNXSV003024971
HMNXSV003046597
Hs.238465.0.S1_3p_at
Hs.238465.0.S1_3p_x_at
Hs.238465.1.S1_3p_at
Hs.238465.1.S1_3p_x_at
ILMN_1761388
ILMN_1783161
ILMN_1808850
PH_hs_0012876
TC09000611.hg
Participates
as a member of
RAS GAPs [cytosol] (Homo sapiens)
Inferred To
gap-2 [cytosol]
(Caenorhabditis elegans)
raskol [cytosol]
(Drosophila melanogaster)
dab2ipb [cytosol]
(Danio rerio)
Dab2ip [cytosol]
(Mus musculus)
Dab2ip [cytosol]
(Rattus norvegicus)
DAB2IP [cytosol]
(Bos taurus)
DAB2IP [cytosol]
(Canis familiaris)
DAB2IP [cytosol]
(Gallus gallus)
DAB2IP [cytosol]
(Sus scrofa)
Cross References
RefSeq
XP_016869789.1
,
XP_011516573.1
,
XP_011516572.1
,
XP_005251776.1
,
NP_115941.2
,
NP_619723.1
OpenTargets
ENSG00000136848
GeneCards
Q5VWQ8
HPA
ENSG00000136848-DAB2IP
Ensembl
ENSP00000386183
,
ENSG00000136848
,
ENST00000259371
,
ENSP00000259371
,
ENST00000309989
,
ENST00000408936
,
ENSP00000310827
PRO
Q5VWQ8
Pharos - Targets
Q5VWQ8
HMDB Protein
HMDBP13782
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.527
2
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.527
2
UniProt:Q99683 MAP3K5
1
MAP3K5 [cytosol]
(R-HSA-167709)
0.508
2
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