Reactome | ASCC1 [nucleoplasm]

ASCC1 [nucleoplasm]

Stable Identifier

R-HSA-5656393

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Activating signal cointegrator 1 complex subunit 1, Trip4 complex subunit p50, ASC-1 complex subunit p50, CGI-18

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8N9N2 ASCC1

Gene Names

ASCC1, CGI-18

Chain

chain:1-400

Reference Genes

BioGPS Gene:51008 ASCC1

COSMIC (genes):ASCC1 ASCC1

CTD Gene:51008 ASCC1

dbSNP Gene:51008 ASCC1

ENSEMBL:ENSG00000138303 ASCC1

HGNC:24268 ASCC1

KEGG:hsa:51008 ASCC1

Monarch:51008 ASCC1

NCBI Gene:51008 ASCC1

OMIM:614215 ASCC1

UCSC:Q8N9N2 ASCC1

Reference Transcript

Participates

as a component of

ASCC1:ASCC2:ASCC3 [nucleoplasm] (Homo sapiens)

Inferred To

ASCC1 [nucleoplasm] (Bos taurus)

ASCC1 [nucleoplasm] (Canis familiaris)

ASCC1 [nucleoplasm] (Gallus gallus)

ASCC1 [nucleoplasm] (Sus scrofa)

ascc1 [nucleoplasm] (Danio rerio)

ascc1 [nucleoplasm] (Xenopus tropicalis)

cg12129 [nucleoplasm] (Drosophila melanogaster)

Ascc1 [nucleoplasm] (Mus musculus)

Ascc1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001185728.1, NP_001185729.1, NP_001185727.1, XP_006717936.1, NP_001356022.1, NP_001356023.1, NP_001356024.1

ENSEMBL

ENST00000317126, ENSP00000339404, ENSP00000320461, ENST00000394915, ENST00000672957, ENSP00000500935, ENST00000342444, ENSP00000378373, ENSG00000138303

OpenTargets

ENSG00000138303

GeneCards

ASCC1

HPA

ENSG00000138303-ASCC1

PRO

Q8N9N2

Pharos - Targets

Q8N9N2

GlyGen

Q8N9N2

Orphanet

ASCC1

PDB

8TLY

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3