Reactome | RHEB [endosome membrane]

RHEB [endosome membrane]

Stable Identifier

R-HSA-5656350

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

Rheb

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15382 RHEB

Gene Names

RHEB, RHEB2

Chain

chain:1-181, propeptide:182-184

Reference Genes

BioGPS Gene:6009 RHEB

COSMIC (genes):RHEB RHEB

CTD Gene:6009 RHEB

dbSNP Gene:6009 RHEB

ENSEMBL:ENSG00000106615 RHEB

HGNC:10011 RHEB

KEGG Gene (Homo sapiens):6009 RHEB

Monarch:6009 RHEB

NCBI Gene:6009 RHEB

OMIM:601293 RHEB

UCSC:Q15382 RHEB

Reference Transcript

RefSeq:NM_005614.3 RHEB

Other Identifiers

0001780397

11716258_at

11716259_at

11716260_s_at

11754028_s_at

1555780_3p_a_at

1555780_a_at

1659_s_at

17064544

201452_at

201453_3p_x_at

201453_x_at

213404_3p_s_at

213404_s_at

227633_at

3079757

3079758

3079759

3079764

3079766

3079768

3079770

3079772

3079774

3079789

3079790

3079791

3244986

3244988

3244989

4037904

4037905

4037907

4037908

56845_at

6009

78322_r_at

7927285

8143957

A_23_P134247

A_33_P3413083

D78132_s_at

GE79454

GO:0000139

GO:0000166

GO:0000287

GO:0003674

GO:0003924

GO:0005515

GO:0005525

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005681

GO:0005737

GO:0005764

GO:0005765

GO:0005773

GO:0005783

GO:0005789

GO:0005794

GO:0005829

GO:0005886

GO:0006914

GO:0006950

GO:0007049

GO:0007050

GO:0007165

GO:0007264

GO:0008150

GO:0009056

GO:0012505

GO:0014069

GO:0016020

GO:0016241

GO:0019003

GO:0019899

GO:0019901

GO:0030154

GO:0032006

GO:0032008

GO:0032991

GO:0034198

GO:0042592

GO:0043167

GO:0043226

GO:0046872

GO:0048714

GO:0048856

GO:0070062

GO:0120163

GO:2000074

HMNXSV003040814

Hs.279903.0.S1_3p_at

Hs.279903.1.S1_3p_at

Hs.279903.2.S1_3p_a_at

Hs.279903.2.S1_3p_x_at

Hs2.279903.2.S1_3p_s_at

ILMN_1657949

PH_hs_0029600

TC07002040.hg

g5032040_3p_a_at

g5032040_3p_x_at

Other forms of this molecule

RHEB [lysosomal membrane]

Inferred To

RHEB [endosome membrane] (Bos taurus)

RHEB [endosome membrane] (Canis familiaris)

RHEB [endosome membrane] (Gallus gallus)

RHEB [endosome membrane] (Sus scrofa)

rhebl1 [endosome membrane] (Danio rerio)

Rheb [endosome membrane] (Drosophila melanogaster)

Rheb [endosome membrane] (Mus musculus)

Rheb [endosome membrane] (Rattus norvegicus)

rheb [endosome membrane] (Dictyostelium discoideum)

rheb-1 [endosome membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_005605.1

OpenTargets

ENSG00000106615

GeneCards

Q15382

HPA

ENSG00000106615-RHEB

Ensembl

ENSG00000106615, ENST00000262187, ENSP00000262187

PRO

Q15382

Pharos - Targets

Q15382

Orphanet

24858

HMDB Protein

HMDBP08547

PDB

1XTR, 6BCU, 1XTS, 1XTQ, 7BTC, 3T5G, 6BSX, 7BTA, 6BT0, 7BTD, 5YXH, 3SEA

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06307 CCK	1	CCK [extracellular region] (R-HSA-388539)	0.556	3
UniProt:Q14957 GRIN2C	3	p-Y-GRIN2C [plasma membrane] (R-HSA-9612189) GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761)	0.556	3
UniProt:P55212 CASP6	5	CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128) CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3