p-8Y-FGFR1b [plasma membrane]

Stable Identifier
R-HSA-5656338
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Fibroblast growth factor receptor 1b, FGR1_HUMAN
Icon
p-8Y-FGFR1b [plasma membrane] icon
p-8Y-FGFR1b [plasma membrane] icon
Locations in the PathwayBrowser
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General
While the existence of a "b" isoform of fibroblast growth factor receptor 1 is well established and its biochemical and functional properties have been extensively characterized (e.g., Mohammadi et al. 2005; Zhang et al. 2006), its amino acid sequence is not represented in reference protein sequence databases, except as the 47-residue polypeptide (deposited in GenBank as accession AAB19502) first used by Johnson et al. (1991) to distinguish the "b" and "c" isoforms of the receptor.
External Reference Information
External Reference
UniProt:P11362-19 FGFR1
Gene Names
FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR
Participates
as a component of
Other forms of this molecule
FGFR1b [plasma membrane]
Inferred To
phospho-p-8Y-FGFR1b [plasma membrane] (Bos taurus)
phospho-p-8Y-FGFR1b [plasma membrane] (Caenorhabditis elegans)
phospho-p-8Y-FGFR1b [plasma membrane] (Canis familiaris)
phospho-p-8Y-FGFR1b [plasma membrane] (Danio rerio)
phospho-p-8Y-FGFR1b [plasma membrane] (Drosophila melanogaster)
phospho-p-8Y-FGFR1b [plasma membrane] (Gallus gallus)
phospho-p-8Y-FGFR1b [plasma membrane] (Mus musculus)
phospho-p-8Y-FGFR1b [plasma membrane] (Rattus norvegicus)
phospho-p-8Y-FGFR1b [plasma membrane] (Sus scrofa)
phospho-p-8Y-FGFR1b [plasma membrane] (Xenopus tropicalis)
Modified Residues
Name
O4'-phospho-L-tyrosine at 463
Coordinate
463
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 583
Coordinate
583
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 585
Coordinate
585
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 653
Coordinate
653
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 654
Coordinate
654
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 730
Coordinate
730
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 766
Coordinate
766
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 776
Coordinate
776
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Interactors (25)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P09038 FGF2  1 0.912 9
 UniProt:P19174 PLCG1  6 0.903 11
 UniProt:P05230 FGF1  1 0.838 5
 UniProt:P46934 NEDD4  1 0.672 26
 UniProt:P51812 RPS6KA3  7 0.671 4
 UniProt:P08238 HSP90AB1  6 0.669 3
 UniProt:P27986 PIK3R1  16 0.644 6
 UniProt:Q8IVI9 NOSTRIN  2 0.633 5
 UniProt:P23352 ANOS1  1 0.626 7
 UniProt:P11362 FGFR1  9 0.623 4
 UniProt:P35222 CTNNB1  20 0.623 3
 UniProt:P21802 FGFR2  20 0.623 3
 UniProt:P08908 HTR1A  1 0.62 9
 UniProt:P10686 Plcg1  8 0.611 4
 UniProt:Q16543 CDC37  1 0.569 4
 UniProt:Q9NQH7 XPP3      0.569 3
 UniProt:Q8WU20 FRS2  6 0.569 3
 UniProt:O35082  2 0.558 2
 UniProt:Q9GZV9 FGF23  6 0.544 2
 UniProt:P22455 FGFR4  12 0.539 3
 UniProt:P12830 CDH1  8 0.536 3
 UniProt:Q7KZF4 SND1  2 0.483 2
 UniProt:P46108 CRK  1 0.483 2
 UniProt:P06493 CDK1  11 0.483 3
 UniProt:O88900  1 0.471 3
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